Immunocal Scientifically Proven To Raise Glutathione GSH Levels
Dr. Allan Somersall M.D - "Immunocal
is the future of the wellness movement - nothing else I
know can impact the ability of every cell in the human body
to defend itself from the common pathological mechanisms.
To raise glutathione
levels is to reduce premature oxidation, to quench destructive
free radicals and help detoxify the poisons inside each
cell when it needs to. Only Immunocal is clinically proven
to do that in a safe, effective and convenient way."
Dr. Jean Marcoux M.D - - "Almost everyone I put on
Immunocal tells me that they feel better as
soon as they start taking the product. This is explained by the
fact that Immunocal brings to all the cells in our body, the building
blocks necessary to produce glutathione, a small, a small protein
that each cell needs to function properly. The need for medication is decreased, they sleep better,
they don't miss work or school as often, resulting in a better quality of life.
Immunocal provides the necessary components of glutathione GSH that,
when absorbed into the body, stimulate the body’s own production
of glutathione to be used by every cell. Immunocal is an all-natural
formula designed to increase intracellular glutathione, one of the
most powerful and most prevalent antioxidants in the body.
terms, this means that Immunocal provides the essential nutritional
building blocks that promote the body's natural ability to fight
inflammation and can help strengthen the immune system.
may be the most important supplement for 21st century mankind. Glutathione
plays a major role in the state of our health and well-being and
longevity. It can increase our production of Glutathione three-fold
and help protect us from a polluted environment. The concentration
of glutathione declines with age and in some age-related diseases.
Robert O. Young D.Sc., Ph.D - "In the last ten years,
over 25,000 medical articles about Immunocal have been published, and the scientific understanding of
glutathione is gradually
becoming common knowledge."
Scientifically Studied: Immunocal is proven and patented to raise glutathione GSH
level. It is a natural source of the glutathione building block called cysteine, that addresses several critical
factors affecting your quality of life and for the maintenance of a strong immune system. Glutathione is the most prevalent, natural,
powerful and multifunctional antioxidant in the human body and is employed by every organ.
Health benefits from regular consumption of Immunocal by Wulf Droge, PhD
The most frequent complaint by far is the difficulty of mixing the
product. Immunocal could be put into capsules, but you would need
to take about 30 to 60 capsules per day to get 10 to 20 grams of
the product...which is not very practical. It cant be made into
a liquid, as the shelf life would go from 2 years to a few months.
It can’t be flavored, or have agents added to it (to improve mixing)
as we have customers with multiple chemical sensitivities who could
not tolerate any additives to the product. The videos just below
demonstrate the best ways to prepare or mix Immunocal.
How to prepare or mix Immunocal
The proteins in Immunocal are very fragile. Do not heat this product or add it to hot liquids. Do not use a high-powered blender
to mix. Heat and severe mechanical action will break down the protein and diminish the usefulness of the product. Immunocal is
a dehydrated powder. It must be rehydrated with liquids before use. If left standing too long after mixing, the usefulness of the product
may be reduced. It is generally recommended to consume the product within 30 minutes of mixing. Special low-speed blenders or mixing
cups can be made available through Immunotec Inc.’s distribution networks.
Do you have a question about holistic animal health or need assistance?
Call 323-522-4521 or 323-989-3372
Immunocal Questions and Answers
What is Immunocal?
is an all-natural non-prescription health product available worldwide.
This special protein holds many national and international patents
and is medically recognized in the Physicians’ Desk Reference (“PDR”
U.S.A.) and Compendium of Pharmaceutical Specialties (“CPS” Canada).
It has undergone over 30 years of research and has been taken safely
and effectively by millions of individuals. Immunocal is also called
Humanized Milk Serum, or HMS-90 in Canada. Top
How to Prepare or Mix Immunocal
Immunocal Global Opportunities
Immunocal acts in two ways – it is a very high quality protein that
provides all the amino acids your body needs, and, more critically,
it raises a substance in your body called “glutathione
Glutathione plays many roles in your body, the four most important
of which can be summarized by the acronym:
AID = E2
Glutathione is the body’s “Master Antioxidant”
System: Glutathione is critical for immune function
Glutathione is your cell's key detoxification enzyme
Glutathione contributes to your overallenergy
at many levels Top
How does Immunocal work?
The Natural Health Products Directorate of Health Canada has issued
an NPN (Natural Product Number) for the specific health claim “Immunocal
is a natural source of the glutathione precursor cysteine for
the maintenance of a strong immune system.” (NPN-80004370)
Immunocal contains specific fragile proteins that supply your
body with the building blocks needed for the production of
glutathione in your
cells. These building blocks are called “precursors” and glutathione
precursors are relatively rare in our normal diets. Unfortunately,
eating glutathione itself does not effectively raise glutathione
in the cells; this is why we need the precursors. Top
Do healthy people need glutathione?
Optimal glutathione levels are important for everyone. Although
you are hopefully in good health right now, glutathione levels fall
as we age, and are lowered by a great number of very common illnesses.
There is a constant demand for glutathione in our daily life; stress,
pollution and infectious disease are all causes of
For those that exercise regularly, glutathione is especially important
to replenish to avoid injury, improve recovery time and keep your
immune system strong. Top
Which illnesses may be affected by raising glutathione?
Many disease states are characterized by low glutathione levels.
Immunocal has been developed as a strategy to help sustain glutathione
levels. Glutathione deficiency
states include, but are not limited to: AIDS and cancer muscle wasting,
chemical and infectious hepatitis, radiation poisoning, malnutrition
states, strong physical stress, and acetaminophen toxicity. Many
other problems including cardiovascular, lung, digestive and kidney
disorders are associated with glutathione deficiency and are cited
in numerous medical references.
Health benefits from regular consumption of Immunocal by Wulf Droge, PhD
Who should avoid Immunocal?
People who have a specific allergy to milk proteins (this is different
from lactose intolerance) need to avoid this product. People who
are taking immunosuppressive medication in the case of organ transplants
should not take this product. Top
Who should be cautious with Immunocal?
People who are on a protein-restricted diet need to calculate into
their daily equation 9 grams of protein per pouch and should not
exceed their daily protein limit. Keep in mind that Immunocal has
a very high “biological value” as a protein and will supply an excellent
source of amino acids for those individuals who may be challenged
Are there side effects and what do I do about them?
Abdominal cramps and bloating can occasionally occur. This is usually
corrected by increasing your fluid intake. Rarely, some individuals
may experience a rash with this product. Although this may indicate
an allergy, it may represent a “detoxification reaction”. In both
cases, discontinuing the product should resolve the symptom. If
any symptoms are severe or persistent, contact your health care
Is Immunocal safe to take with medication?
There have been no known harmful side effects of using Immunocal
or any other Immunotec product while on medications. However, to
be safe, it is suggested to consult with your physician if you have
any questions. Top
How much should I take and when should I take it?
a natural source of the glutathione cysteine precursor for the
maintenance of the good health, 10 grams per day (one pouch) is
recommended. As a natural source of the glutathione cysteine precursor
for the maintenance of a strong immune system, 20 grams per day
is recommended (two pouches). Clinical trials in patients with AIDS,
chronic obstructive pulmonary disease (COPD), cancer and chronic
fatigue syndrome have used 30 - 40 grams per day without ill effect.
Immunocal is best administered on an empty stomach or with a
light meal. Concomitant intake of another high protein load may
adversely affect absorption. Top
Do you have a question about holistic animal health or need assistance?
Call 323-522-4521 or 323-989-3372
How many packages are in one box of Immunocal?
here to order at discount price There are thirty (30) packages of Immunocal in every box. This is
the same for Immunocal or Immunocal Platinum.
How do I store Immunocal?
Try to keep Immunocal in a cool dry place. Avoid prolonged exposure
to hot environments. Refrigeration will prolong the life of the product but is optional. Top
What is Immunocal Platinum?
More Valuable than GOLD!
Immunocal has been Immunotec’s flagship product for years. Immunocals’
action is based on the benefits of raising glutathione. The wealth
of research on glutathione and the aging process speaks for itself.
What is it about the “Platinum” formulation that takes this a step
further? Let’s examine this closer.
The major impact on your health that Immunocal bestows is by
providing the building blocks or “precursors” for your cells to
be able to make glutathione. This is a technology that we continue
to refine. Both Immunocal and Immunocal Platinum represent the only
patented protein proven to do this. In the development of Immunocal
Platinum, we have looked very carefully both at protein metabolism
and at potential components of whey proteins that relate to aging.
Two separate formulations have been added to Immunocal – CMP™* and
CMP (Cytokine Modulating Peptides)
Cytokines are little molecules that the immune system uses to
regulate inflammation. Inflammation plays a role not only in issues
like aches and pains, but also in cardiovascular and neurological
health. Inflammation has been pointed to as one of the key factors
driving the aging process. What CMP does, is “turn down the volume”
on these cytokines.
*CMP is a trademark of Glanbia LLC. Top
RMF (Redox Modulating Formula)
RMF is an exclusive development from Immunotec’s research and
development team mastered by Dr. Wulf Dröge. The major objective
here was to decrease the amount of acid formed in the body (important
to the kidneys), and as a second benefit, reduces the amount of
calcium lost (important in bone health). Top
Who should take Platinum?
We all should take Platinum. Although it was initially developed
with the “Baby-Boomers” and geriatric populations in mind, it became
clear that there were benefits for overweight individuals, athletic
individuals, people with circulation challenges and others. Certainly,
good old Immunocal has proven benefits for all these groups, but
Platinum represents the next generation in immune enhancement and
will become the new standard in the immune health market. The recommended
serving size is unchanged from Immunocal and it can be combined
with Immunocal as desired. Top
Turn a triple into a HOME RUN!
Immunocal Platinum provides a triple action on your immune health
– Raising glutathione represents Preventative immunity, the cytokine
modulating proteins representing Reparative Immunity. Attention
to the proper acid-base balance helps lead to Sustained Immunity.
Turn this triple into a homer by topping it off with the other supplements
your health professional may recommend to you! Top
What is the difference between Immunocal and Immunocal Platinum?
Immunocal naturally boosts glutathione levels in the human cell,
helping the immune system to perform at optimal levels. The Platinum
product contains the same glutathione-enhancing ingredients as Immunocal,
but was designed specifically for baby boomers. Among its many features,
Immunocal Platinum works with the body to repair damaged cells and
to improve mood, energy, well-being, alertness, concentration and
clarity, all important to the maturing population. It also helps
maintain proper muscle function and maintain bone health by reducing
calcium loss. learn more
Does Immunocal contain any additives?
The product is additive-free; the sole ingredient is undenatured whey protein isolate.
Can a person who is lactose-intolerant take Immunocal?
Yes, since each pouch of Immunocal contains less than 1% lactose,
it is usually well-tolerated in people who are lactose-intolerant.
It should be noted that being lactose-intolerant is different than
having a milk protein allergy. Top
How does the manufacture of Immunocal differ from other whey proteins?
Immunotec’s proprietary manufacturing process preserves the critical
disulfide bonds in the glutathione precursor cysteine. By delivering
this delicate protein to the cell, it enables the body to create
glutathione and maximize immune system levels. Other whey proteins
are often manufactured using extreme heat and harsh methods of mixing,
resulting in a denatured and ineffective product. Top
What are the Immunocal/Immunocal Platinum pouches made of, and are they recyclable?
The pouches are made of low-density polyethylene; the Immunocal Platinum pouch also contains foil layers. The pouches are not recyclable.
What does undenatured mean?
Immunocal works by providing important glutathione precursors to
the cell. It is critical that these precursors remain intact or
undenatured during the manufacturing and mixing processes in order
to enhance the immune system. That is why the manufacture (Immunotec)
recommend that Immunocal not be heated or subject to harsh mixing
in order to preserve its bioactivity. Top
What is the difference between Immunocal and other whey proteins?
While other whey proteins may be good sources of nutrition, only
Immunocal is proven to raise glutathione levels and enhance the
immune system. Immunocal has a proprietary and unique formulation
developed by Immunotec who uses a proprietary manufacturing process
for its production.
Why can’t glutathione be taken in pill form?
Glutathione is produced by the body in the cell when the necessary
precursors are provided. Immunocal delivers cysteine to the cell
so that it can produce glutathione. Pills pass through the digestive
system and little, if any, glutathione is absorbed.
Where can I find Immunocal listed?
Immunocal is listed in the Physicians’ Desk Reference, the Pharmacist’s
Red Book and is eligible for coverage under Medicare/Medicaid in the U.S. In Canada, it is listed in the
Compendium of Pharmaceuticals and Specialties (CPS).
What patents does Immunocal hold?
Immunocal has been awarded numerous method of use patents for the
prevention and treatment of cancer, the treatment of HIV, as an
immune system enhancer, for its ability to raise glutathione, and
as a chemotherapeutic agent. Top
here to order at discount price
Can Athletes Safely Benefit from Immunocal?
Yes. Immunocal has been tested as part of ConsumerLab.com’s Athletic
Banned Substance Screening Program which screens for over 170 substances
(including metabolites) based on the 2007 World Anti-Doping Code
Prohibited List and has been certified free of any prohibited substances.
The screening includes testing for stimulants, narcotics, anabolic
agents, diuretics, masking agents and beta blockers based on the
Olympic Movement Anti-Doping Code or the codes of other sports organizations.
Immunocal information on
Private Insurance coverage and Medicare/Medicaid in the U.S.
Is bioactive whey protein reimbursed by Medicare, Medicaid and Private Insurance programs?
Yes. Although Medicare and Medicaid do not endorse or "approve" any company's product, an Immunocal bioactive
whey protein meets the coding determination for coverage eligibility by Medicaid, Medicare, and many private insurance programs. Although
the purchase of bioactive whey protein does not require a doctor's prescription, a prescription is required for reimbursement eligibility
coverage under Medicare and Medicaid. NOTE: The Immunocal bioactive whey protein is the FIRST product sold by any direct selling company
in the world to ever meet these strict criteria. This is a phenomenal accomplishment for a non-drug "nutritional supplement", and clearly
establishes a higher level of validation and credibility for this product!
The Immunocal bioactive whey protein has
it's own NDC (National Drug Control) registry number: 28770-0970-01,
and is being approved on a state-by-state basis for reimbursement.
The code for Medicare is: B4155. Currently, Ohio, New Jersey,
Minnesota, Nevada, and New York have established reimbursement guidelines,
and decisions in 18 states are currently pending. In some of these
states (notably New York State and California), this bioactive whey
protein is available without restriction on Medicaid. In other states,
the physician must be willing to write a letter of necessity in
addition to writing a prescription for it to be reimbursed. It meets
the requirements for enteral nutritional supplements which are eligible
for coverage by Medicare/Medicaid for nutritional management of
the patient. This is available for general practitioners to prescribe.
For Medicare patients, current coverage eligibility is limited to
Naso-Gastric (NG) tube feedings, but Medicaid is much less restrictive.
Medicaid has broader prescribing parameters for both oral as
well as tube-feeding nutritional management. This
Immunocal bioactive whey protein will be one
of the few nutritional supplements to be listed in the year 2000
through 2009 edition of the prestigious Physicians' Desk Reference
(PDR). Physicians have relied on the PDR for up-to-date information
on prescription drugs for over 50 years. The PDR is considered the
standard prescription drug reference and can be found in virtually
every physician's office, hospital, and pharmacy in the United States.
The inclusion of this product in the PDR is a reflection of it's
credibility within the medical community, and is also a result of
our recognition by Medicare and Medicaid. For questions regarding
reimbursement procedures in your State, please contact your State
Medicaid agency or Medicare plan contractor, or contact your private
insurance plan provider directly.
here to order Immunocal bioactive whey protein at discount price
Private Insurance Coverage
Individuals should contact their private healthcare insurance company to inquire whether Immunocal is covered if prescribed by their healthcare
professional. Reimbursement will follow your insurance company’s usual protocol.
Reimbursement by State
Please see the below chart for general information. Please note, Medicaid program requirements are subject to change. Healthcare
providers and patients should check with their state Medicaid agency to obtain current coverage and billing requirements to ensure compliance
with state requirements.
Covered - Often priced by individual claim, frequently needs prior approval
Reimbursed by calorie content
- Missouri – may need “exception” form
- New Jersey
- New York
- North Dakota
- Virginia – AIDS only
- Wisconsin – AIDS, wasting, Cystic Fibrosis
Coverage follows Medicare Guidelines - Tube feeding only
- New Mexico
- Illinois – AIDS & Cancer only
- Louisiana – may need “Exception” Form and must represent
70% of calorie intake some cases under 21 would cover orally
- Idaho – Children only for oral and reimbursed by
Immunocal code not covered
- Hawaii – also reimburses by calorie as well
- Iowa – Children only for oral and also there is disease
- Kentucky – Might try “Exception” Form
- Maryland – Disease restrictions
- South Carolina
- South Dakota
- Texas – May cover children orally
- Washington DC
- Alabama – Children may be given special consideration
- Arkansas – Children only
- California – TAR form
- Georgia – Oral is only children under 21
- Kansas – Reimbursed by calorie as well
- New Hampshire
- Mississippi – May cover children orally
- North Carolina
- Oklahoma – Children may be given special consideration
- Puerto Rico
- Rhode Island – May cover children orally, disease
- West Virginia
All Medicare/Medicaid business is handled by the Medical Division’s
Distribution Group. Since it is government reimbursement it must
be handled this way so as not to be in violation of anti-kickback
Q. What is Immunocal bioactive whey protein? What is HMS-90?
A. Immunocal is a specific brand of bioactive whey protein (which is also
called Humanized Milk Serum, or HMS-90 in Canada). There are several other
brands of bioactive whey proteins, but at the time of this writing, none
of these brands are backed by clinical research. Immunocal is not a prescription
drug, but a patented (8 Method of Use Patents world-wide, and 5 US Patents)
un-denatured and bio-active whey protein dietary supplement that is rich in glutathione precursors.
These US patents include:
Biologically active whey protein concentrate,
Biologically active undenatured whey protein,
Undenatured whey protein concentrate to improve active systemic humoral
Method of treatment of HIV-seropositive individuals with dietary whey proteins,
Anti-cancer therapeutic compositions containing whey protein concentrate,
Use of a decapeptide with benzodiazepine-type activity for preparing medicines
and food supplements
Immunotec invested over $10 million and 18 years of research into their
product, which is extremely rare for a non-prescription nutritional supplement.
The primary researcher involved in the discovery of Immunocal bioactive whey protein is
Gustavo Bounous, MD. Immunocal bioactive whey protein is a highly concentrated
milk serum isolate which is high in protein (90% protein by weight) and
is lactose-free, carbohydrate and sugar-free, and fat-free. Immunocal shares
many of the same immune promoting and enhancing properties of Mother's milk.
Immunocal has been clinically proven to increase serum and tissue
glutathione levels, and is validated by extensive research, including
numerous published scientific studies and review articles which appear
in the medical literature and are available for you to examine through our
MEDLINE (National Library of medicine) link. Immunocal increases glutathione,
which is your cells' own natural antioxidant and most potent detoxifier.
Immunocal has been demonstrated to enhance both healthy and deficient immune
systems, and is validated as an effective nutritional supplement by the
medical community. Immunocal is the only non-prescription dietary supplement
to appear in the year 2000 through 2008 Physician's Desk Reference (PDR)
for Prescription Drugs, although it is available without prescription! It
has it's own NDC (National Drug Control) number, and is reimbursable under
Medicaid, Medicare, and by private insurance in many states.Top
here to order at discount price
Q. Is Immunocal bioactive whey protein approved by the
FDA for the treatment of cancer, chronic fatigue, autoimmune, and glutathione
A. No. The United States Food and Drug Administration (FDA) does not "approve"
any nutritional supplements for these indications. The FDA determines the
safety of nutritional supplements, and regulates or restricts the distribution
of those products considered to pose a health risk to the American public.
Immunocal is considered to be "generally recognized as Safe", (GRAS) by
the FDA. This is the same classification given vitamin C. Based on a recent
decision by the US Court of Appeals for the District of Columbia Circuit,
the FDA is tolerating references to certain therapeutic uses of nutritional
supplements which are based on
strong scientific or clinical evidence and "significant scientific agreement".
Because Immunocal bioactive whey protein is manufactured by a Canadian company,
the manufacturer is more sensitive to the regulatory pressures of the FDA
than American supplement manufacturers, and has chosen to be ultra-conservative
in their marketing of the product. Each box of the product is produced from
500 liters (125 gallons) of fresh, organic milk from free-range, grass-fed
cattle on a contract farm in the state of Idaho. No disease treatment claims
are made concerning bioactive whey protein. Top
Q. What is the difference between Immunocal bioactive whey protein and
other whey proteins?
A. Immunocal bioactive whey protein has been shown to differ from other
whey proteins in its effect upon the immune system. Specifically,
studies on other whey proteins have not shown the same immune
stimulating effects that are seen with bioactive whey protein. Immunocal
bioactive whey protein has been
extensively studied in the clinical literature.
Immunocal bioactive whey protein to other commercial whey proteins clearly
shows the superiority of bioactive whey protein. Immunocal bioactive whey
protein is one of 4 commercially available bioactive whey proteins, but
it is the only one that is supported by eighteen years of research and by
both animal research and human clinical trials. Bioactive whey protein studies
(done with Immunocal) have shown that they not only increase intracellular
levels of GSH (glutathione or glutathione precursors) following ingestion,
but also significantly build up the stores of these substances inside the
cells. This beneficial effect lasts for considerable periods of time after
ingestion of bioactive whey protein. Top
Q. What is the product's bioactivity dependent upon?
A. Concentrations of 3 bioactive and thermolabile (easily damaged by heat)
proteins that are contained in the milk serum: serum albumin, alpha lactalbumin
and lactoferrin. Because these compounds can be damaged by heat (in excess
of 140 degrees F) or excessive mechanical agitation, bioactive whey protein
must not be cooked, heated, or placed in a steel-bladed blender. For these
reasons, and to preserve the bioactivity of its serum albumin, alpha lactalbumin
and lactoferrin, bioactive whey protein has not been exposed to standard
high-temperature Pasteurization. Rather, it has been bio-filtered to remove
bacteria, and subjected to patent-process low-temperature purification procedures
to ensure its safety and purity. Top
Q. If a different manufacturer of whey protein supplements was able to
duplicate Immunotec's technology, could they make the same claims?
A. No. The method of use
patents preclude another manufacturer from duplicating the manufacturing
process of Immunocal. Immunotec Immunocal bioactive whey protein patents
(presently there are eight patents on bioactive whey protein: 5 US patents,
and 3 international patents) relate to the METHOD OF USE. That is, no other
whey protein can state: "clinically PROVEN to stimulate the immune system",
and "significantly raises glutathione levels". Additionally, although there
are dozens of companies producing denatured (high-heat Pasteurized)
whey proteins (primarily for use as a protein source in body-building),
there currently is no company manufacturing an UNDENATURED whey protein
product similar to Immunocal bioactive whey protein.
Numerous clinical studies and medical reviews appear in the clinical
literature which specifically involved the Immunocal brand of bioactive
whey protein, and not other high-heat pasteurized commercial whey proteins.
Accept no imitations. Top
Q. What exactly is glutathione and how is it important?
A. Glutathione is the master antioxidant of the body. Without glutathione,
we die. The replenishment of the glutathione levels within the lymphocytes
(also called leucocytes or white blood cells) increases the intensity of
the immune response. The increase in glutathione levels also results in
the proliferation of lymphocytes that act as a scavengers, and helps to
combat infections. Selenium (a micronutrient and mineral) is a structural
component of, and a co-factor for the antioxidant enzyme glutathione peroxidase.
For this reason, supplementation with selenium can modestly increase glutathione
levels in persons who are selenium deficient. Glutathione is a tri-peptide
of the amino acids cysteine, glycine, and glutamic acid. Tissue glutathione
levels increase when cystine levels increase within the cell. This is why
cystine is critical in the production of glutathione, but prior to the development
of bioactive whey protein, no effective way was known to safely and significantly
increase cystine levels in the cell over long periods of time. A deficiency
of glutathione can cause hemolysis (the destruction of red blood cells resulting
in severe anemia) and numerous diseases of oxidative stress. Low glutathione
levels are commonly found among the elderly, those undergoing cancer chemotherapy,
and among patients suffering from autoimmune and immune deficiency diseases
such as rheumatoid arthritis, chronic fatigue syndrome (CFSIDS), fibromyalgia,
and AIDS. Glutathione is essential in intermediary metabolism as a donor
of sulfhydryl groups (which are essential for the detoxification of the
liver). That is why the only known "side effects" associated with bioactive
whey protein supplementation are associated with the beneficial detoxification
which occurs as a result of improved liver function. The antioxidant enzyme
glutathione peroxidase functions in the process of elimination of wastes
from the body. Glutathione works within the liver, lungs, colon, kidneys,
and skin in the process of removing toxic eliminating cellular metabolic
Q. What is the difference between products or pills that people use as
supplements that are labeled as "glutathione" or "cystine"?
A. Glutathione is produced within the cells (intra-cellularly). When taking
a pill labeled "glutathione", clinical and laboratory studies demonstrate
that oral glutathione is NOT absorbed but will be eliminated by the liver
through the bile before ever reaching the systemic circulation (blood stream).
Cystine is not well absorbed when taken by mouth. Injectable glutathione
also has limited benefits. It is unstable in the blood stream. By the time
it gets to the cell, much of it gets degraded, and much of this remaining
glutathione cannot effectively pass through the cell membrane.
Clinical studies have demonstrated that oral cystine supplementation
(NAC or N Acetyl L-Cysteine) is NOT effective in increasing cystine levels
within the cell, and has also not been associated with significant increases
in glutathione levels within the cell. The three bioactive proteins
supplied by bioactive whey protein constitute a "natural delivery system"
from these cystine precursors to the cell (in order to facilitate clinically
and statistically significant increases in glutathione levels in BOTH
the extracellular serum and intracellular tissues). Because Immunocal bioactive
whey protein provides the building blocks for cystine, and these building
blocks for cystine are easily transported inside the cell where they can
be quickly synthesized into glutathione, bioactive whey protein is therefore
ideally suited to increase glutathione levels within the cell.
Q. What is the difference between NAC (N Acetyl L-Cysteine) and bioactive
A. N Acetyl L-Cysteine (NAC) is sulfur-containing (sulfhydryl) amino acid
which is present in many proteins, and is in the same class as the amino
acid methionine. NAC is a naturally occurring amino sugar and is a form
of cysteine which has been demonstrated to facilitate the SHORT TERM cellular
detoxification of alcohol, tobacco smoke, acetaminophen [Tylenol®] poisoning
and environmental pollutants in several in vitro studies. When Cystine is
heated, molecular bonds are cleaved and it becomes Cysteine.
Cysteine is beneficial if it is produced INSIDE the cell, but is mildly
toxic if it is produced outside the cell. NAC does not travel well in the
blood stream, and doesn't reach the cells (to be used to synthesize glutathione
and Glutamic acid). NAC supplementation over long periods has been associated
with modest increases in serum glutathione, but has not proven particularly
useful in the treatment of chronic, long-term intracellular glutathione
deficiencies. Furthermore, therapeutic levels of NAC are relatively toxic
and have been associated with significant side effects. At therapeutic doses,
oral NAC supplementation has been associated with cerebral symptoms, nausea,
blurred vision, and vomiting. Immunocal bioactive whey protein provides
the precursors for the manufacture of intra-cellular cystine, and effectively
delivers these to the cell. For this reason, bioactive whey protein supplementation
has been associated with sustained and significant increases of cellular
glutathione, and is virtually devoid of troublesome side-effects. Bioactive
whey protein has the same side-effect profile as mothers' milk.
Q. What is the difference between bovine colostrum and bioactive whey
A. The proteins in colostrum have almost no cystine content. Cystine is
critically essential to the immune system. Although Growth Factors present
in colostrum (including IGF-1, or Insulin-like growth Factor-1 which is
effective in promoting muscle growth) are not affected by stomach acid,
research published by one manufacturer of Colostrum (Vital Health News,
Winter 1998, page 7) demonstrated that "the effectiveness of the immune
factors present in colostrum is lowered by stomach acid." Although the
immune enhancing factors found in colostrum are often "preferable to single
isolated immune components" (such as interferon, which is more likely to
cause troublesome side effects), colostrum has NOT been demonstrated to
be superior to isolated undenatured whey proteins such as Immunocal bioactive
whey protein. Colostrum (which is produced during the first 26 hours following
birth by the mammary glands) is primarily composed of immunoglobulin and
some lactoferrin. According to both laboratory experiments and clinical
trials conducted in Germany, although colostrum supplementation was associated
with mild increases in immune function in some patients, these increases
were not statistically significant, (p=ns). A postulated mechanism
of action of colostrum is the inter-species transfer of immune factors,
however this has NOT been clinically proven. Most of the data supporting
the effectiveness of colostrum is anecdotal (consisting mostly of personal
testimonies rather than clinical studies). Since the primary mechanism of
action on the immune system is via stimulation of the synthesis (production)
of glutathione, the near absence of glutathione precursors in the immunoglobulin
fraction (from the colostrum) may explain its relative lack of effect. Conversely,
bioactive whey protein contains substantial amounts of thermolabile (heat-sensitive)
proteins that are rich in cystine and glutamylcystine (known precursors
of glutathione), and Immunocal bioactive whey protein has been validated
in numerous human clinical
trials which found statistically significant increases in glutathione
and indices of immune function (such as CD4:CD8 ratios). Colostrum might
be beneficial as an adjunctive (add-on) to bioactive whey protein, but the
clinical data is significantly more convincing for bioactive whey protein.
Q. How does the manufacturing of Immunocal differ from other whey proteins?
A. In the manufacturing of other whey proteins several things occur: in
the process of heating and Pasteurization, critical bonds holding the cystine
together get broken down ("denatured", meaning they lose their original
nature--similar to the denaturing and irreversible changing of liquid egg
white by the heating process involved in frying an egg). The exact type
of proteins that serve to increase tissue and serum glutathione most effectively
are lost or diminished. Researchers have developed a process by which these
delicate proteins remain intact in their natural form to serve us most effectively.
Q. Is Immunocal bioactive whey protein free from Bovine Growth Hormone,
antibiotics, and other chemicals?
A. rBGH (bovine Growth Hormone) and other growth hormones have become a
major issue of controversy in the dairy industry. Certain herdsmen give
their cows the growth hormone to increase milk production. It is devastating
to the cows, and to those who drink their milk also. American dairy farmers
in the state of Idaho provide the milk to manufacture Immunocal bioactive
whey protein from one large dairy farm in the state of Idaho. This particular
location was chosen because the soil selenium levels are highest in the
USA, and grazing on grasses which are grown on Idaho selenium-rich soil
results in high selenium levels in the milk. Selenium (an essential micronutrient
and mineral) is a structural component of the powerful "master antioxidant"
glutathione. The selenium level in 10 grams of bioactive whey protein is
more than 4 mcg, which is much higher than found in most commercial whey
proteins. That is good. This facilitates the cystine component of the whey
protein (bioactive whey protein is 100% whey protein) from this selenium-rich
milk to be more effeciently metabolized by the body to form glutathione
within the cells of the body. On the other hand, absolutely no herbicides,
pesticides or chemicals are used on the grasses these cows graze upon. The
milk from these cows qualifies to be certified organic (hormone, pesticide
and agricultural chemical-free). The cattle on this farm are subjected to
more rigorous standards than almost any other dairy cattle in the USA. If
a cow is sick and must be treated with antibiotics (or any other pharmaceutical
compound), it is removed from the herd and its milk is not used. Absolutely
no BGH or other hormone compounds are used on these cows. Top
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Q. What are some additional benefits of whey proteins?
A. Immunocal bioactive whey protein has been clinically demonstrated to
increase exercise capacity by 13 percent (Lands
et al., 1999), and may be useful as a supplement for competitive athletes.
Wattanabe et al. (Japan) conducted a clinical study with bioactive
whey protein to evaluate increases in GSH among patients with Hepatitis
B and C, and found that these viruses are vulnerable to glutathione. In-vitro
studies in Japan also showed that whey can stimulate the bone cell (osteoblasts) to produce more bone,
hence increasing bone density and reducing the risk of osteoporosis.
Glutathione (from whey protein) lowers serum cholesterol by stimulating
bile synthesis in the liver. In addition, glutathione is a powerful antioxidant
that will prevent lipid peroxidation (a sign of free radical activity).
Lipid peroxidation is implicated in arteriosclerosis (hardening of the arteries),
stroke and coronary artery disease. Lactalbumin
from whey protein has been
demonstrated to kill breast cancer cells in vitro (in a test-tube). Because neither bioactive whey protein
nor glutathione is a drug, no disease treatment claims can be made on the
basis of these studies. Top
Q. What is the theoretical mechanism of action of GLUTATHIONE in Cancer
and Immune dysfunction?
A. Natural killer (Immune) cells may become glutathione-depleted over time,
and immune response weakens. Bioactive whey protein raises glutathione levels
and strengthens the immune system. The immuine system is the body's first
line of defense against cancer, viruses, bacteria, etc. For those patients
receiving traditional medical therapy for their cancer, bioactive whey protein
supplies lactalbumin and has been clinically proven to raise glutathione
lactalbumin (a component of bioactive whey protein) have been associated
with the strengthening of healthy cells and (paradoxically) the weakening
of cancerous cells. In research conducted by C. Svanborg et al, lactalbumin
was associated with
apoptosis (or the programmed death) of breast cancer cells. Glutathione
has been scientifically demonstrated to decrease cancerous cells' resistance
to chemotherapeutic drugs, while protecting healthy cells. This would theoretically
allow a patient to respond better to chemotherapy with less side effects.
Because neither bioactive whey protein, lactalbumin, nor glutathione is
a drug, no disease treatment claims can be made on the basis of these studies.
Q. What are the diseases or conditions that have been associated with
low glutathione levels?
A. Most of the autoimmune and degenerative diseases of aging including:
Acetaminophen poisoning, ADD, Addison's Disease, aging, AIDS, Alopecia Areata,
ALS, Alzheimers' Disease, anemia (hemolytic), Ankylosing Spondylitis, Arteriosclerosis
(hardening of the arteries), arthritis (rheumatoid), asthma, autism, autoimmune
disease, Behcet's Disease, burns, cacexia, cancer, candida infection, cardiomyopathy
(idiopathic), Chronic Fatigue Syndrome, colitis, coronary artery disease,
cystic fibrosis, diabetes, Crohn's disease, eczema, emphysema, Epstein Barr
Viral (EBV) syndrome, fibromyalgia, free radical overload, Goodpasture Syndrome,
Graves' Disease, hepatic dysfunction (liver disease), hepatitis B, hepatitis
C, hypercholesterolemia (high blood cholesterol), herpes, infections (viral,
bacterial and fungal), inflammatory bowel disease (IBD), lupus, macular
degeneration (diabetic macular degeneration), malnutrition, Meniere's disease,
multiple sclerosis, Myasthenia Gravis, neurodegenerative diseases, nutritional
disorders, Parkinson's disease, Pemphigus Vulgaris, Primary Biliary Cirrhosis,
progeria, psoriasis, Rheumatic Fever, Sarcoidosis, scleroderma, shingles,
stroke, surgery, toxic poisoning, trauma, vasculitis, vitiligo, and Wegener's
Granulomatosis. No disease treatment claims can be made for glutathione
on the basis of glutathione deficiency in these diseases. Top
Q. Has therapy to increase glutathione levels been effective in treating
the diseases or conditions that have been associated with low glutathione
Medline Search Page (replace the 5 Xs with the name of the disease you
want to research). Please remember that because glutathione is not a prescription
drug (except the injectable form) no disease treatment claims can be made
for glutathione on the basis of glutathione deficiency in these diseases.
Q. Can a person who is lactose intolerant take Immunocal bioactive whey
A. Yes, certain brands. Immunocal bioactive whey protein has less than 1%
lactose which should not cause any ill effect even in the most severe case
of lactose intolerance.
Q. Can a person who is intolerant of Monosodium Glutamate (MSG) take
bioactive whey protein?
A. Yes, Immunocal bioactive whey protein has NO added MSG (trace amounts
may occur naturally) which should not cause any ill effect in people with
an MSG intolerance. Bioactive whey protein contains the following amount
of glutamic acid by weight: 180 mg/gram. There is therefore 1.8 grams of
glutamic acid in a 10 gram packet of bioactive whey protein. Every single
protein on the earth contains glutamic acid, and glutamic acid is required
for good health. Glutamic acid is an amino acid formed in the digestion
of ALL proteins (including wheat gluten and meat). It is the only amino
acid metabolized by the brain. Glutamic acid is necessary in human nutrition
but can usually be manufactured by the body in adequate amounts. That means
that our own body produces it. In certain disease states, deficient diet,
malnutrition, and in certain metabolic abnormalities this amino acid becomes
conditionally essential. Glutamic Acid's sodium salt, is monosodium glutamate,
and ALL proteins may contain naturally occurring trace amounts of MSG. In
summary, bioactive whey protein would not supply any more glutamic acid
than a serving of steak or other similar protein. There is NO added MSG
in bioactive whey protein, and its supplementation should not cause a medical
problem in a persons sensitive to MSG. Top
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Q. Are there any interactions known between supplements such as coenzyme
Q-10, antioxidant vitamins, or herbs and bioactive whey protein?
A. No, there are no known potential or reported interactions between bioactive
whey protein and nutritional supplements. In fact, bioactive whey protein
increases glutathione levels, which helps to improve the action of
antioxidant vitamins (which are less effective if your glutathione levels
are impaired). For this reason, mega-doses of antioxidant vitamins (i.e.
doses in excess of 10 times the RDA of these vitamins) are not required
or recommended if you are supplementing with Immunocal bioactive whey
protein. As we age, our glutathione levels fall precipitously like a down-hill
ski-slope. Low levels of glutathione
are associated with a host of degenerative diseases, and critically
low levels of serum and tissue glutathione often predict that death is imminent.
Supplementation with bioactive whey protein helps restore these precious
glutathione levels, and helps the supplemental vitamins we are taking to
work more effectively to maintain optimum health! Because neither bioactive
whey protein, nor glutathione is a drug, no disease treatment claims can
be made on the basis of these findings. Top
Q. Are there any interactions known between prescription medications
and Immunocal bioactive whey protein?
A. No, there are no known interactions between bioactive whey protein and
prescription drugs. Bioactive whey protein is composed of the same basic
proteins which are found in human breast milk, and should be considered
to be as safe to take as mothers' breast milk. Furthermore, bioactive whey
protein is 90% protein, and is one of the best sources of highly-absorbable
protein on the planet. Patients taking immunosuppressant drugs such as Cyclosporin®
should consult their physician before taking bioactive whey protein.
Q. Are there any side effects associated with bioactive whey protein?
A. Bioactive whey protein increases serum and liver glutathione levels.
When liver glutathione levels rise, the liver is able to more effectively
detoxify the body (which is a beneficial function of bioactive whey protein).
Some people (especially those who have been exposed to high levels of environmental
toxins) may have a mild temporary reaction to these mobilized toxins as
the liver is removing them from storage in body fat. Typically, reducing
the dose of bioactive whey protein will allow these temporary side effects
to quickly disappear. Bioactive whey protein is composed of the same basic
proteins that are found in human breast milk, and has the same side effect
profile as mothers' breast milk. Because bioactive whey protein is a milk
protein, persons who are mildly allergic to milk proteins may experience
minor gastric distress from bioactive whey protein. This gastric distress
usually disappears if you reduce the dose. Persons with serious milk-protein
allergies should not take bioactive whey protein Top
Q. Can you overdose bioactive whey protein? Is there any potential for
toxicity if you take too much?
A. Your greatest risk is wasting your money if you take "too much" bioactive
whey protein, since it is relatively expensive. Scientific data suggests
that there is limited benefit from exceeding 3 grams per day (3 packets
per day) of bioactive whey protein. Because our cells have an innate mechanism
of "feed-back inhibition" with respect to the glutathione synthesis precursors
(building blocks) provided by bioactive whey protein, there is no potential
for making "too much glutathione" within the cell if large quantities of
bioactive whey protein are consumed. Bioactive whey protein supplementation
will result in establishment of normal glutathione levels, (NOT excessive
glutathione levels) within the cell. Excess bioactive whey protein would
be metabolized as protein (whey protein is an excellent source of protein,
containing 90% protein by dry weight). Top
Q. Because Immunocal bioactive whey protein is 90% protein, is it contraindicated
in patients on renal dialysis who must limit protein intake?
A. No, bioactive whey protein is not contraindicated in these patients.
Although we suggest that you consult your personal physician with medical
questions such as these, there is no reason to believe that bioactive whey
protein would be harmful in these patients. Bioactive whey protein is one
of the most easily digested and most easily absorbed forms of protein in
the diet. Its Protein Efficiency Ratio (PER: a mark of the quality of a
protein) is extremely high, and in conditions such as renal failure
where protein intake must be limited, it is most prudent to consume the
highest quality proteins such as whey proteins and egg white proteins, versus
lower quality proteins that produce more problematic metabolic waste by-products
Q. Is bioactive whey protein contraindicated in Celiac Sprue disease?
A. No. These patients are usually instructed not ingest wheat or gluten.
There is no wheat, or gluten found naturally in bioactive whey protein.
Furthermore, at least one brand of bioactive whey protein (Immunocal) is
lactose-free. There is no reason to believe that that Immunocal bioactive
whey protein would be detrimental in patients with Celiac Sprue.
Q. Who should not take the product?
A. People with an allergy specifically to milk protein, (which is very rare).
NOTE: Please understand that lactose intolerance is NOT a milk allergy.
Also, anyone who has had an organ transplant and is receiving immunosuppressant
therapy should not take bioactive whey protein unless instructed to do so
by his or her physician or another health care professional. The immune
system needs to be suppressed in order to prevent organ rejection, and bioactive
whey protein may counteract immunosuppressant medicines such as cyclosporin®.
Q. What are some of the critical ingredients in a daily amount of Immunocal
bioactive whey protein (1 pouch)?
A. 9 grams or 90% Protein, 0 Fat, less than 0% Lactose, 60 mg of Calcium,
4 micrograms of Selenium, 30 Mg of Potassium, 0.05 mg of Iron, and approximately
40 Calories. Top
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Q. What is the recommended dose for taking Immunocal bioactive whey protein?
A. Check with your physician or health care professional. If you do not
have a documented glutathione deficiency and are taking bioactive whey protein
to maintain good health, one pack per day is not unreasonable. Generally,
most studies conducted using bioactive whey protein in patients with glutathione
deficiencies used at least 20 grams per day (2 pouches), and some studies
showed increased effectiveness using up to 30 grams (3 pouches) per day.
Most people use 2 boxes per month (this provides 2 pouches, or 20 grams
per day per month).
Q. What is the recommended intake of protein for an average adult per
day? A. 50-60 grams of protein. Three packets of bioactive whey protein
would provide 50% of this recommended daily intake. Top
Q. What is the difference in taking Immunocal bioactive whey protein
as opposed to taking antioxidants?
A. Vitamin E and C are important antioxidants, and you should consider these
important supplements in your diet. Bioactive whey protein is not an antioxidant
per se, but provides the building blocks for the synthesis of glutathione,
which is THE principle intra-cellular antioxidant. Glutathione is the most
potent cellular antioxidant known to man, and is hundreds of times more
potent than vitamin C or vitamin E. For this reason, glutathione has been
called the "Super Antioxidant". By raising the glutathione level within
our bodies we provide for the optimum functioning of other lesser antioxidants
such as vitamins C and E. More importantly, glutathione serves as a detoxifying
agent for multiple toxins that we encounter on a daily basis through the
environment and medications we are exposed to. Glutathione has been demonstrated
to act as an effective protectant against ultraviolet radiation, which is
important in view of the continued loss of the ozone layer.
Q. How much does Immunocal bioactive whey protein cost?
A. Immunocal is available from the manufacturer or manufacturer's representatives
for as little as $59.40/box.
Q. Is there a test to determine if my glutathione levels are low?
A. Yes. We know of a
laboratory that charges only $40 for this test. DISCLAIMER: We
are NOT associated with this laboratory, nor do we receive ANY reimbursement
from recommending their services.
Q. Is Immunocal bioactive whey protein listed in the Physicians Desk
A. Yes. Immunocal bioactive whey protein produced from organic USA cow's
milk and manufactured and processed in the United States is the ONLY nutritional
product sold by direct sales to be listed in the prestigious
which is also frequently called the "physician's bible", and is owned and
consulted by virtually every physician in the USA and world-wide! Physicians
have relied on the PDR for up-to-date information on prescription drugs
for over 50 years. The PDR is considered the standard prescription drug
reference and is found in virtually every physician's office. Although this
brand of bioactive whey protein does NOT require a prescription, it's inclusion
in the PDR is a result of recognition by the medical community, of the extensive
clinical data supporting it's effectiveness, and as a result of it's recognition
by Medicare and Medicaid as reimbursable. The publisher of the PDR,
Medical Economics, also produces a smaller companion volume for non-prescription
drugs and herbal medicines. This volume may contain references to other
bioactive whey proteins and other nutritional supplements.
Q. What is the best way to mix Immunocal?
A. Because bioactive whey protein is a very fine and delicate powder, the
manufacturer recommends mixing it with water or any juice or liquid that
is not above lukewarm (less than 110 degrees F, and NEVER above 120 degrees
F) temperature. First, mix the packet with approx. 1 tablespoon of the liquid
you have chosen to form a paste. Second, now pour the liquid to fill your
glass. Allow it to sit for a few minutes, stir, and enjoy. It can also be
mixed in applesauce, yogurt, or sprinkled over cereal without any particular
mixing procedure. The product CANNOT be mixed in a blender (mechanical mixing
damages the milk proteins). You must stir by hand, or you can purchase an
Q. How can I order Immunocal?
A. The most economical way is to select "ImmunoDirect monthly autoship program".
You will get the lowest discount and can cancel at any time--even the following
week--without penalty or obligation. Most folks chose to continue to receive
Immunocal on a monthly basis, conveniently shipped to their home the same
time each month. Top
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Do you have a question about holistic animal health or need assistance?
Call 323-522-4521 or 323-989-3372
"Antioxidants are well documented and known to possess vital roles in health
maintenance and disease prevention.
Glutathione is your cell's
own major antioxidant. Maintaining elevated glutathione levels aids the
body's natural antioxidant function." - Biochemical Pharmacology 47: 2113-2123
may or may not have heard of glutathione, even though over tens of thousands
of medical articles have highlighted its importance. Optimizing glutathione
levels will shortly join the list of factors known by everyone to have an
impact on our health and well-being.
Learn more about Glutathione, the
Most Powerful Antioxidant, Plays a Critical Role in the Cellular Detoxification
Utilization of GSH. Research has shown that individuals who have
low levels of glutathione are susceptible to chronic illness. Research shows
that GSH levels (glutathione) decline by 8% to 12% per decade, beginning
at the age of 20. Levels of glutathione are further reduced by continual
stress upon the immune system such as illness, infection, and environmental
toxins. As we now know, a lowered immune system can bring about illness
and disease. This is a ferocious cycle. While you need glutathione for a
productive immune system, a weakened immune system hampers the production
of glutathione. Supplements Containing Glutathione Alone Will NOT Increase
The Body’s GSH Levels. It is pointless to purchase supplements that merely
contain glutathione, because the digestive system breaks down ingested glutathione
and it will not be absorbed into your system. On the other hand, Immunocal
provides the proper nutrients needed to promote the body's own ability to
manufacture and absorb glutathione. Immunocal also aids in liver support
by destroying environmental poisons helping the liver to function as the
main production site and storehouse for glutathione.
Glutathione, educational information
- Patrick J.D. Bouic, Ph.D - "No
other antioxidant is as important to overall health as glutathione.
It is the regenerator of immune cells and the most valuable detoxifying
agent in the body. Low levels are associated with early aging and
Glutathione has three important functions: It serves as an
Antioxidant, an Immune system enhancer and a Detoxifier.
- As an antioxidant, glutathione (often abbreviated as
GSH) is the most powerful antioxidant that protects against free
radical damages or “oxidative stresses,” which have been implicated
in a number of illnesses such as heart disease, cancer, diabetes
and even the negative effects of aging.
- As an immune system enhancer, glutathione is needed for
the proper functioning, and in particular the creation and maintenance,
of T-cells lymphocytes, the body’s front-line defense against infection.
- As a detoxifier, dozens of toxins are eliminated by the
glutathione enzyme system, including heavy metals, cigarette smoke,
fuel exhaust and other carcinogens
Clinical results documented an average increase of 292% in intercellular
Glutathione levels for persons taking Immunocal for 60 days. Amazingly,
the same report showed an average increase of 46% of DHEA and 40.8%
for IGF-1, both markers related to levels of human growth hormone, the
indicators of true biological age. Furthermore, TNF improved 37%. TNF
(Tumor Necrosis Factor alpha) is one of the three most significant markers
of cellular inflammation.
In an unrelated study, researchers recently discovered that Centenarians
between the ages of 100 to 105 years of age have Glutathione levels
similar to 30-50 year old well, physically fit, healthy individuals.
Does increased Glutathione levels in your body help you live longer?
Given the choice, I think I would rather have an ample supply of Glutathione
in my body than be Glutathione deficient.
benefits of taking Immunocal include the following:
Better quality of sleep.
Improved mental focus.
Decreased aches and pain
Glutathione for Health and Energy
Glutathione is the most powerful antioxidant and antitoxin in your body.
Increasing Glutathione levels will naturally increase your energy, detoxify
your body and strengthen your immune system. Glutathione is a protein
produced naturally in our cells. Unfortunately, as we grow older our
body produces less and less of this vital health compound. It is our
major defense system against illness and aging.
Our Glutathione levels indicate our state of health and can predict
longevity. Glutathione is used by every cell in our body. It doesn't
matter if it is a cell in your big toe, a heart muscle cell, or a brain
cell. All cells must have ample quantities of Glutathione to function
normally and stay healthy and generate energy.
Glutathione for Wellness and Living Longer
Glutathione improves mental functions, improves concentration, increases
energy, promotes increased levels of exercise, helps chronic pain disorders,
lowers blood pressure, improves heart and lung functions, and helps
control the effects of diabetes. Increasing age and other factors
reduce the body's production and utilization of Glutathione. Research
has shown that individuals who have low levels of Glutathione are susceptible
to chronic illness and a myriad of medical problems.
data indicates our Glutathione levels decline by 8% to 12% per decade,
begriming at the age of 20. Levels of Glutathione are further reduced
by continual stress upon the immune system such as illness, infection,
and environmental toxins and pollutants. A lower immune system results
in higher incidents of illness and disease. This condition is a ferocious
cycle. While you need Gluathione for a productive immune system a weakened
immune system hampers the production of Glutathione. Supplements that
only contain Glutathione will not increase the body's Glutathione. It
is useless to purchase supplements that merely consists of only Glutathione,
because the digestive process destroys ingested Glutathione.
Immunocal provides the proper nutrients (precrusors) needed to get
through the stomach and into the blood to generate Glutathione. Immunocal
also aids in liver support by destroying enviromental poisons and pollutants
thus helping the liver to function as the main production site and storehouse
eat over-processed food that is devoid of nutrients and laced with pesticides
and herbicides. We drink water polluted with industrial toxins and heavy
metals. We breathe air polluted with toxic fumes and then we expect
our body to function normally. Most of us live in an environmental nightmare—a
toxic chemical soup. Our body tries to cope the best it can; however,
the low quality food we eat, and the polluted air and water we consume
endangers our health and longevity.
The human body was not built to process pollutants and food crammed
with chemical preservatives and stripped of vital nutrients. Emotional
and medical stress, and environmental toxins create free radicals as
our body tries to fight these health hazards. These hazards constantly
bombard our natural defenses and can eventually deplete our internal
supply of Glutathione. The end result is low energy, disease, and medical
impairments ranging from heart disease, diabetes, cancer and even premature
Decreases in brain Glutathione levels induced by Sleep Deprivation
Department of Psychobiology, Universidade Federal de Sao Paulo, Escola
Paulista de Medicina, Sao Paulo, Brazil.
findings from this laboratory revealed that sleep deprivation reduces
total glutathione GSH levels in hypothalamus, suggesting an increased
vulnerability to oxidative damage. These results confirm that sleep
deprivation reduces hypothalamic GSH…
The objective, therefore, was to study glutathione content in the
liver, heart, and lung, because glutathione is considered a major free
radical scavenger that reflects the degree to which a tissue has been
oxidatively challenged. We also investigated major enzymatic antioxidants,
including catalase and glutathione peroxidase, as well as indexes of
glutathione recycling. Catalase activity and glutathione content, which
normally are tightly regulated, were both decreased in liver by 23–36%
by 5 and 10 days of sleep deprivation.
Such levels are associated with impaired health in other animal models
of oxidative stress-associated disease. The decreases were accompanied
by markers of generalized cell injury and absence of responses by the
other enzymatic antioxidants under study. Enzymatic activities in the
heart indicated an increased rate of oxidative pentose phosphate pathway
activity during sleep deprivation. Recovery sleep normalized antioxidant
content in liver and enhanced enzymatic antioxidant activities in both
the liver and the heart. The present results link uncompensated oxidative
stress to health effects induced by sleep deprivation and provide evidence
that restoration of antioxidant balance is a property of recovery sleep.
Food Sources That Boost Glutathione Naturally
By Priya Shah
Copyright © 2004 Priya Shah
the body's master antioxidant and detoxifier, is one of the 14 "Superfoods"
listed in SuperFoods Rx : Fourteen Foods That Will Change Your Life,
co-authored by Dr Steven Pratt. Glutathione levels cannot be increased
to a clinically beneficial extent by orally ingesting a single dose
of glutathione. (1) This is because glutathione is manufactured inside
the cell, from its precursor amino acids, glycine, glutamate and cystine.
Hence food sources or supplements that increase glutathione must
either provide the precursors of glutathione, or enhance its production
by some other means. The manufacture of glutathione in cells is limited
by the levels of its sulphur-containing precursor amino acid, cysteine.
Cysteine - as a free amino acid - is potentially toxic and is spontaneously
catabolized or destroyed in the gastrointestinal tract and blood plasma.
However, when it is present as a cysteine-cysteine dipeptide, called
cystine, it is more stable than cysteine. Consuming foods rich in sulphur-containing
amino acids can help boost glutathione levels. Here are some food sources
and dietary supplements that help boost glutathione levels naturally.
1. N-Acetyl-Cysteine (NAC) It is derived from the amino acid L-Cysteine,
and acts as a precursor of glutathione. NAC is quickly metabolized into
glutathione once it enters the body. It has been proven in numerous
scientific studies and clinical trials, to boost intracellular production
of glutathione, and is approved by the FDA for treatment of accetaminophen
overdose. Because of glutathione's mucolytic action, NAC (brand name
Mucomyst) is commonly used in the treatment of lung diseases like cystic
fibrosis, bronchitis and asthma.
2. Milk Thistle, Silymarin Milk thistle is a powerful antioxidant
and supports the liver by preventing the depletion of glutathione. Silymarin
is the active compound of milk thistle. It is a natural liver detoxifier
and protects the liver from many industrial toxins such as carbon tetrachloride,
and more common agents like alcohol.
3. Alpha Lipoic Acid Made naturally in body cells as a by-product
of energy release, ALA increases the levels of intra-cellular glutathione,
and is a natural antioxidant with free radical scavenging abilities.
It has the ability to regenerate oxidized antioxidants like Vitamin
C and E and helps to make them more potent. ALA is also known for its
ability to enhance glucose uptake and may help prevent the cellular
damage accompanying the complications of diabetes. It also has a protective
effect in the brain.
4. Natural Foods That Boost Glutathione Levels Asparagus is a leading
source of glutathione. Foods like broccoli (2), avocado and spinach
are also known to boost glutathione levels. Raw eggs, garlic and fresh
unprocessed meats contain high levels of sulphur-containing amino acids
and help to maintain optimal glutathione levels.
5. Undenatured Whey Protein Isolate Whey protein contains proteins
like alpha-lactalbumin which is is rich in sulphur-containing amino
acids. Heating or pasteurization destroys the delicate disulphide bonds
that give these proteins their bioactivity. Undenatured whey protein
is a non-heated product that preserves bioactive amino acids like cystine.
It has been shown in numerous scientific studies and clinical trials
to optimize glutathione levels.
6. Curcumin (Turmeric) Treatment of brain cells called astrocytes,
with the Indian curry spice, curcumin (turmeric) has been found to increase
expression of the glutathione S-transferase and protect neurons exposed
to oxidant stress. (3)
7. Balloon Flower Root Changkil saponins (CKS) isolated from the
roots of the Chinese herbal medicine, Platycodon grandiflorum A. DC
(Campanulaceae), commonly called Balloon Flower Root or Jie Geng, have
been found to increase intracellular glutathione GSH content and significantly
reduce oxidative injury to liver cells, minimise cell death and lipid
8. Selenium Selenium is a co-factor for the enzyme glutathione peroxidase.
Selenium supplements have become popular because some studies suggest
they may play a role in decreasing the risk of certain cancers, and
in how the immune system and the thyroid gland function. However, too
much selenium can cause some toxic effects including gastrointestinal
upset, brittle nails, hair loss and mild nerve damage. Disclaimer: The
information here is not provided by medical professionals and is not
intended as a substitute for medical advice. Nutritional supplements,
while usually benign, can produce adverse reactions in some people.
As with prescribed drugs, long-term effects from supplements are often
unknown. Pregnant women and children should not take supplements except
after consultation with their health care provider. Never exceed the
recommended dosage on the container. If you observe adverse effects
stop taking the supplement immediately and contact your health care provider.
1. The systemic availability of oral glutathione Witschi A, Reddy
S, Stofer B, Lauterburg BH. [Eur J Clin Pharmacol. 1992;43(6):667-9.]
2. Dietary approach to attenuate oxidative stress, hypertension,
and inflammation in the cardiovascular system Wu L, Ashraf MH, Facci
M, Wang R, Paterson PG, Ferrie A, Juurlink BH. [Proc Natl Acad Sci U
S A. 2004 May 4;101(18):7094-9. Epub 2004 Apr 21.]
3. Can Curry Protect Against Alzheimer's? American Physiological
Society (APS) Press release; 16-Apr-2004
4. Protective effect of saponins derived from roots of Platycodon
grandiflorum on tert-butyl hydroperoxide-induced oxidative hepatotoxicity
Lee KJ, Choi CY, Chung YC, Kim YS, Ryu SY, Roh SH, Jeong HG. [Toxicol
Lett. 2004 Mar 7;147(3):271-82.] This article was first published in
the July 2004 issue of The Glutathione Report, a newsletter featuring
regular updates on the health benefits of glutathione. Get a Free report
on Glutathione in Health and Disease Article Source: http://EzineArticles.com/?expert=Priya_Shah
1. Bounous G, Stevenson MM, Kongshavn PAL. Influence of dietary lactalbumin
hydrolysate on the immune system of mice
and resistance to Salmonellosis. J Infect Dis 144: 281, 1981.
2. Bounous G, Letourneau L, Kongshavn PAL. Influence of dietary protein
type on the immune system of mice. J Nutr 113:
3. Bounous G, Kongshavn PAL. Influence of protein type in nutritionally
adequate diets on the development of immunity. In:
Absorption and Utilisation of Amino Acids. M. Friedman (Ed.). Boca Raton,
Florida: CRC Press, vol. 2, 219-32, 1989.
4. Bounous G., Batist G, Gold P. Immunoenhancing property of dietary
whey protein in mice: role of glutathione. Clin Invest
Med 12: 154-61, 1989.
5. Bounous G, Shenouda N, Kongshavn PAL, Osmond DG. Mechanism of altered
B-cell response induced by changes in
dietary protein type in mice. J Nutr 115: 1409-17, 1985.
6. Bounous G, Papenburg R, Kongshavn PAL, Gold P., Fleiszer D. Dietary
whey protein inhibits the development of
dimethylhydrazine-induced malignancy. Clin Invest Med 11: 213-7, 1988.
7. Papenburg R, Bounous G, Fleiszer D, Gold P. Dietary milk proteins
inhibit the development of dimethylhydrazine-induced
malignancy. Tumor Biol 11: 129-136, 1990.
8. Bounous G., Batist G., Gold P. Whey proteins in cancer prevention.
Cancer letters 57, 91-94, 1991.
9. Bounous G, Baruchel S, Falutz J, Gold P. Whey proteins as a food
supplement in HIV seropositive individuals. Clin Invest
Med 16: 204-209, 1993.
10. Baruchel S, Viau G, Olivier R, Bounous G, Wainberg M.A. – Nutriceutical
Modulation of Glutathione with a Humanised
Native Milk Serum Protein Isolate, Immunocal®.
11. Application in AIDS and Cancer. In: Oxidative Stress in Cancer,
AIDS, and Neurodegenerative Diseases. Ed. L.
Montagnier, Olivier R., Pasquier C. Publ Dekker M., New York, 447-461,
12. Lands L, Grey VL, Smountas AA. The Effect of Supplementation with
a Cysteine Donor on Muscular Performance. Journal
of Applied Physiology Vol. 87: 1381-1385, 1999.
13. Lotian B, Grey V, Kimof RJ, Lands L. Treatment of Obstructive Airway
Disease with a Cysteine Donor Protein Supplement:
A Case Report. Chest; 117: 914-916, 2000.
The Immunotec health-promoting products are the fruit of almost
two decades of medical research spearheaded by Dieter Beer, one
of the Immunotec founders and a businessman with a long track record,
and Dr Gustavo Bounous, considered the father of whey protein research.
These two eminent professionals created Immunotec Research Corp.,
a pure research company, which conducted over 18 years of research
that is the foundation of our products.Immunocal Medical Research
The Immunotec business plan is created with one thing in mind…your
success. You will be building your business with a proven system
that gives you the support you’ll need to achieve your individual
goals. The Immunotec business is based on science-based products
that provide results and customer loyalty which turn into referrals.
Whether you would like to earn a little extra income or you are
planning future dreams…the Immunotec opportunity is the vehicle
to get you there.
As a business, their compensation plan is fairly standard. It
is considered a hybrid, with more than one element of other plans
built into it. You can sponsor as many frontline consultants as
you want, and need at least three evenly built "legs" to move up
in the plan, 4 at the higher levels. The plan pays out at 47% with
full compression, and pays down 8 levels of compensation.
Sign up now A personalized educational website and shopping cart is available to each distributor at no charge. - Call Shirley
for more information 323-522-4521 or 323-989-3372
Opportunity Overview: Starting your own home-based business is just a step
Once you sign up as an Immunotec Consultant, make sure you enroll
in Autoship right away to get up to 6 free products and big additional savings.
Customize your Autoship order by selecting the exceptional products that
most suit your needs. Then get your bonuses!
Sign up now