Transfer Factors and the Immune Response in
Animal Health Care
Dr. Steven Slagle, DVM - "A cat with Leukemia, an oral
tumor, and posterior paralysis due to a spinal tumor was very
ill and emaciated. One month after starting her on transfer factors there was some regression of the oral tumor,
restored appetite with some weight gain, and increased sociability. Five
months later, this cat continues to improve - she regained her normal weight,
her oral tumor has regressed 80%, and she has regained the use of her hind legs and tail."
Transfer Factor in Veterinary Application: Canine, Feline, Equine and Livestock
Simply stated, transfer factors are tiny molecules that are able to convey
immunity information from one entity to another to educate naïve cells about
a present or potential danger along with a plan for action. Although the
mostly notable function of these smart molecules is to speed up the recognition
phase of an infection making the duration of an illness much shorter, transfer
factors also have the ability to suppress an over active immune system.
All said, transfer factors have the ability to balance out the function
of your immune system, whether it needs to increase in function or be reduced
in the case of auto-immune disorders.
Richard H. Bennett, Ph.D - "For decades, the approach to maintaining
healthy animals was to wait for signs and symptoms of disease to occur and to
counter the challenge with an array of drugs which were toxic for the disease
causing agent. This approach is now being questioned as the armada of drugs
is diminishing due to multiple drug resistant pathogens. Compounding this alarming
trend is the current approach to health maintenance which assumes that "all
is well" until actual disease processes begin. By this time, the disease is
established, sometimes irreversibly, and the damage has occurred. So the questions
arises...What if a new paradigm existed? Could it be possible to optimize the
immune status of animals so that (1) disease is much less likely to occur and
(2) if disease does occur, it's severity and duration is minimized? The answer
is YES and this paradigm shift is being engineered by small, naturally occuring
protein-like molecules called TRANSFER FACTORS." Dr. Richard Bennett holds a
doctorate in Comparatie Pathology from the University of California, Davis.
His work in this area includes basic and applied research in infectious disease
microbiology and immunology.
Vaccinations may even contribute to premature death in animals whose immune systems were
already compromised, some veterinarians believe. "I had two situations where
we had spent a long time building up two older, severely immunocompromised dogs,
and then their owners had them vaccinated for just about everything known to
man," recalled Dr. Carvel Tiekert, executive director and founder of the American
Holistic Veterinary Medical Association headquartered in Bel Air, Maryland.
"Both of those dogs died within about a month of vaccination. Can we prove a
cause and effect? No. Do I think there was a cause and effect? Yes."
What do Professionals say about Transfer Factors?
Dr. Joe Ramaekers, DVM - "Transfer factors are truly the missing link
in the nutritional approach to preventive practice for all pets. It
is a powerful immune system activator that has the ability to boost the
immune system in an entirely different way."
Question to Dr. Falconer: does vaccination (or over-vaccination)
causes overactive immune reaction (autoimmune disorder) or does it cause
suppression of the immune system?
Dr. Will Falconer D.V.M: "The answer is YES. Probably both. Vaccination
'confuses' the immune system, as I point out in my heartworm eBook.
So, it could go either way, or alternate over time between the two. Transfer factors are natural nutritional supplements
that help support the animal's immune system. A healthy immune system is
capable of helping the body heal itself. Transfer factors should be given
before and immediately after vaccination for at least a few weeks to help
ameliorate the confusion (when someone is faced with a mandatory vaccination,
or has decided they want to give one). By giving the immune system with
Transfer factors, the immune intelligence should be able to better sort through
the confusion, though I'm not sure that's measurable."
Dr. Sam Jones, DVM - "Transfer factors has been a remarkable addition
to my veterinary practice. It is an amazing immune booster that provides
support for so many conditions that animals have."
"A four month old kitten had a severe skin condition that was diagnosed as ringworm. After four
months of conventional therapy, the resistant ringworm infection was not
resolved. We put the kitten on transfer factors and within 5 days there
were no apparent ringworm lesions remaining. Within a few weeks all the
hair had grown back - and the now 9 month old cat has a beautiful, glossy
coat. The ringworm lesions have not returned."
"Two cats, both about 8 years old, had severe diabetes. It was impossible to get the insulin requirements adjusted.
They had lost weight to a point that they were skin and bones. Both cats had
no quality of life left. After one week of being on transfer factors, we were
able to get their insulin requirements adjusted. It is now six months later
and they have both regained their weight, and have a great quality of life and health."
Dr. William Hennen, Ph.D. - "Transfer factors make up a highly concentrated
immune messaging system, designed by nature to transfer immune programming from
one individual to another, both human and animal alike." "Transfer factors are
the most exciting discovery in immunology. As the 21st Century unfolds, transfer
factors will be one of our greatest keys to health and well being."
Dr. Richard Bennett, Ph.D. - "Bacterial infections, viral infections and immune
system fatigue cause a host of disease problems in pets, especially in very
young and older animals. Transfer factors naturally provides full immune system
power and is a natural and science based product for the health of all our animal friends."
Dr. Bennett is an Infectious Disease Microbiologist and Immunologist
Deadly, Contagious Dog Flu Virus
Important Note from Shirley:
Around the world people and veterinarians are using transfer
factors for their large and small animals. Transfer factors is a powder in small capsules which can easily be given to
animals who are too sick to eat. It is easy to shove the capsule into
the throat, or empty the content into the pet's food. Some people mix the
powder with a little water and squirt it into the animal's throat with an ear syringe.
Dr. Cynda Crawford, an immunologist at the University of Florida's College
of Veterinary Medicine who is studying the virus, said that it spread most easily
where dogs were housed together but that it could also be passed on the street,
in dog runs or even by a human transferring it from one dog to another. Kennel
workers have carried the virus home with them.
Independent Study - Transfer factors were tested for their ability
to increase Natural Killer Cell (NK) activity. The researchers used peripheral
blood mononuclear cells (PBMC) isolated from human volunteers. Test results
showed that Transfer factors boosted NK cell activity 103% above normal
immune response without supplementation, more than two times higher than
the next highest product. The study also showed that transfer factors increased
the NK cell activity over 430% above normal immune response without supplementation,
or about five times higher than any of the other previously tested products.
How to buy Transfer Factor at Discount Price
Do you have a question about transfer factors or need assistance?
Call 323-522-4521 or 323-989-3372
Dogs, Distemper, And Transfer Factors
Dr. Baruch Rosen, M.D
"As a physician of nearly thirty years, I was well aware that no antibiotic
would protect against the ravages of viral disease, particularly canine
distemper which shows similarities to HIV. My seven month old white haired
Shepard was adopted from a local shelter and was initially joyful and healthy.
Within three weeks he developed coarse bronchitis with heavy mucus drainage
of the nose and eyes. Our well intentioned vet believed the problem to be
kennel cough and started antibiotics. Over the next ten days Romeo failed
to improve, but instead experienced seven hard and long grand mall seizures
in one weekend, a partial paralysis of the hind quarters which made him
fall flat when attempting to walk and a "spaced-out gaze" of non-recognition.
Blood studies confirmed distemper and showed a white cell count (lymphocytes)
of only 264 slightly more than ten percent of normal. Our vet a second out-of-state
consulting vet, an expert in distemper were very sympathetic and advised
me to prepare myself to euthanize Romeo."
"The heartache was compounded when Chico, my thirteen month old Chihuahua
developed similar symptoms of hard coughing and heavy mucus drainage from
the eyes. Reviewing his shot record, I learned he was mistakenly given only
one distemper immunization, leaving him inadequately protected; and by licking
Romeo's mucus and drinking from his water dish had contracted the infection."
"Knowing little to nothing about canine distemper, I turned to the internet
and luckily stumbled on to transfer factors, a preparation which enhances and stimulates the body's own
immune system to fight against all pathogens, viral or otherwise. My thirty
years in medicine told me this was the only solution. I hurriedly became
a distributor to get the product and started Chico and Romeo on one cap
daily encased in one teaspoonful of raw hamburger. Over the next two weeks
all cough and mucus drainage ceased. Romeo's follow-up blood count had risen
to normal range at 2217 and he surprised the whole family by jumping a five
foot wall. He romps and plays all day long with Chico, now responds normally
to his name and appears to be his old joyful self again."
"Having witnessed the recoveries of Chico and Romeo, and after further
study, all family members are taking transfer factors, one cap daily; our
insurance policy to protect against a faltering immune system, the inevitable
consequence of aging and exposure to environmental
pollution and toxins. As for my distributorship status, I fully intend to
spread the word to all my colleagues and good friends."
Dr. Baruch Rosen, M.D.
Transfer Factors for Horses and Livestock
Dr. Molly Metz, DVM, Lexington, Kentucky
- A 3-yr-old warmblood with history of chronic cough and nasal discharge
was unresponsive to antibiotics. Within two weeks of being on transfer
factors, both the nasal discharge and cough went away. This colt is
being maintained on a maintenance dose of transfer factors.
- A 19-yr-old late gestation mare had stringhalt, ataxia, and moderate
ear droop. I began the mare on transfer factors to improve its immune
function prior to foaling. After 30 days of being on the TF, this mare had no evidence of stringhalt or ataxia, and only a
mild ear droop. This is the first time in her life she was able to pull
her ear forward in a normal position. She also is cushionoid and suffered
miserably in last summer's heat, being unable to sweat. This spring, when
temperatures reached 80 degrees, she was sweating in the field.
- I had a 2I had a 2-year-old thoroughbred filly with a history of multiple bone
pain and suspected neurological condition. This filly was diagnosed with
physitis in multiple bones (via bone scan) and as a wobbler on radiographs.
I placed her on the transfer factors to see if she could be improved enough
to go into training. The farm has begun breaking her and her movement has
improved by approximately 80%. I am waiting to hear if the farm feels she's
good enough to go to the track.
9-yr- old Friesian Gelding Recovers from Severe Dermatitis
9-yr- old Friesian gelding developed severe dermatitis in January 2001. The gelding went from being a beautiful black
horse with full mane and tail to having huge bald spots all over his body. He lost his entire mane and most of his tail.
Our vet, Mike Marrinan, visited twice weekly to do Betadine scrubs and he put Prince on antibiotics. Dr. Marrinan took
biopsies and sent them to two universities. He spoke with numerous specialists, but none could tell us what was wrong.
Our last resort was to put him on steroids. His lesions gradually cleared and his hair started to grow back. By the summer of 2001
we were again riding Prince; however, it became evident that the
steroids were negatively affecting him.
He was not holding his weight and became spooky and unpredictable.
In the fall of 2001 Dr. Marrinan decided to gradually take him off steroids. Two weeks after he concluded steroid
use, a fresh lesion appeared on his face. His immune system was severely compromised, White blood count was 3000
(normal is 15,000). He developed a chronic eye infection and then really got sick. His fever spiked, he became depressed, and
stopped eating and drinking. Dr. Marrinan tried Sulfa drugs and IV's for three days. He put him on Naxel; nothing worked.
Prince had given up; we were sure he was dying. I came across an article in The Horse regarding the immune system.
It spoke of a product called transfer factors. Upon finding an ad for the product I called
Dr. Marrinan and asked him about it. He said, "try it, nothing else is working."
I got a two week allotment of transfer factors. We didn't want to commit to more;
we had already spent thousands of dollars on Prince. There comes a time when you have to be realistic and say enough is enough.
After ten days on the TF Animal Stress Pack, brightness came back into Prince's eyes which we hadn't seen in months.
His appetite increased and he was drinking water again. I called my friend and ordered transfer factors horse formula.
After two weeks his coat started getting glossy again and his appetite returned. Two and a half months later he is fully recovered!
He is playing in the field again; his mane and tail are growing back; his dermatitis is gone; and his eyes are bright and clear!
It is so awesome to see Prince running across the field kicking up his heels with his pasture pals!
I truly believe that transfer factors has saved Prince's life.
The following are testimonies from Lisa Hampton, Trainer, in Montana:
- I had a 9-yr-old quarter horse mare named Annie. She started colicking on a Sunday and was suffering from a severe compaction.
It became obvious by the second day that we were not dealing with a normal colic. She was showing some neurological signs
and her temperature would bounce from 96 to 102. Our vet, Mike Marrinan, came out every day to tube her with mineral
oil and give her IVs. Her blood test showed her liver and kidney functions were off, as was her blood count.
On day three her gums were bright fuschia, her pulse was 78 and her capillary refill time was 4 seconds;
we thought we were going to lose her. Day four she started passing stools. Day five she got severe diarrhea.
The diarrhea and depression lasted for five days. She lost about 200 pounds and her coat turned coarse and dull.
She had patches of skin that were sloughing and her extremities were swelling, including her face. All of these were
signs that she was fighting something toxic. I started her on transfer factors for horse formula and ordered transfer factors
for animals in stress. After four days of being on that she started eating aggressively, jigged to the pasture, and her eyes
were bright and clear. She has put most of her weight back on. Annie was 30 days pregnant when she colicked,
you can't imagine our joy when we did a 65-day ultrasound and saw her fetus doing back flips.
We continue to feed Annie transfer factors throughout her pregnancy. I am convinced that transfer factors is
helping her body fight and the probiotics are aiding in the digestion and healing her gut.
- I had a six-week old quarter horse foal. Monday morning I entered the stall and the foal was lying down looking depressed.
The mare has a swollen udder; obviously the foal was not eating. The foal's temperature was 102.5. Whenever a foal gets
sick it makes you feel so helpless, as they can dehydrate quickly and really go downhill fast. I immediately made a
paste with transfer factors, sulfa tabs, and electrolytes. I gave the paste to the foal both morning and night, and milked out
the mare to keep her comfortable. On day two, the foal had severe diarrhea and was still not eating, and was still depressed.
I continued giving the transfer factors horse formula and antibiotics. Day four I had to chase the little guy down to paste him.
His temperature was 99 and he was nursing again; he had no diarrhea. On day five you would have never known the foal had been
sick. He was running and playing and, remarkably, had lost no weight. I continued to paste him for seven days.
I have never had a foal recover this quickly from fever and diarrhea...and no vet bills.
How to buy Transfer Factors at Discount Price
Equine Protozoa Myeloencephalitis EPM and Transfer Factors
A new paradigm for the treatment and prevention of infections and stress induced immune suppression
R.H. Bennett Ph.D
Introduction: EPM and other chronic diseases of horses and other mammals
have a pattern of wide geographic exposure to significant proportions of
an animal population, yet a small subset of the exposed progress to clinical
disease. This proportionality suggests that other modifying factors have
a major role in disease expression. The case in point here is EPM. There
is wide environmental exposure, as evidenced by seroconversion, yet only
1 to 2 percent become clinically affected. The phenotype of the individual
most likely is a major determinant.
Horses that are highly genetically selected for performance or type
traits most likely lose genetic potentials for robust immune responsiveness,
as is the case for most species. Those individuals that experience the
stressors of transportation and training may then present a phenotype that
is immunologically stress sensitive. This subset is apparently small, but
may be the group most likely to succumb to immune challenges like that
of EPM. The question then is how can the immune abilities of the animal
be supported to restore these phenotypic challenges?
Neurologic disease in horses caused by Sarcocystis neurona is difficult
to diagnose, treat, or prevent, due to the lack of knowledge about the
pathogenesis of the disease. This in turn is confounded by the lack of
a reliable equine model of equine protozoal myeloencephalitis (EPM). Epidemiologic
studies have implicated stress as a risk factor for this disease, thus,
the role of transport stress was evaluated for incorporation into an equine
model for EPM. Sporocysts from feral opossums were bioassayed in interferon-gamma
gene knockout (KO) mice to determine minimum number of viable S. neurona
sporocysts in the inoculum. A minimum of 80,000 viable S. neurona sporocysts
were fed to each of the nine horses. A total of 12 S. neurona antibody
negative horses were divided into four groups (1-4). Three horses (group
1) were fed sporocysts on the day of arrival at the study site, three horses
were fed sporocysts 14 days after acclimatization (group 2), three horses
were given sporocysts and dexamethasone 14 days after acclimatization (group
3) and three horses were controls (group 4).
All horses fed sporocysts in the study developed antibodies to S. neurona
in serum and cerebrospinal fluid (CSF) and developed clinical signs of
neurologic disease. The most severe clinical signs were in horses in group
1 subjected to transport stress. The least severe neurologic signs were
in horses treated with dexamethasone (group 3). Clinical signs improved
in four horses from two treatment groups by the time of euthanasia (group
1, day 44; group 3, day 47). Post-mortem examinations, and tissues that
were collected for light microscopy, immunohistochemistry, tissue cultures,
and bioassay in KO mice, revealed no direct evidence of S. neurona infection.
However, there were lesions compatible with S. neurona infection in horses.
The results of this investigation suggest that stress can play a role in
the pathogenesis of EPM. There is also evidence to suggest that horses
in nature may clear the organism routinely, which may explain the relatively
high number of normal horses with CSF antibodies to S. neurona compared
to the prevalence of EPM.
2. Serum antibodies to West Nile virus in naturally exposed and vaccinated
horses Louis A. Magnarelli1, Sandra L. Bushmich2, John F. Anderson1, Michel
Ledizet3 and Raymond A. Koski3 J Med Microbiol 57 (2008), 1087-1093
1 Connecticut Agricultural Experiment Station, New Haven, CT 06504,
USA 2 Department of Pathobiology and Veterinary Science, University of
Connecticut, Storrs, CT 06269, USA 3 L2 Diagnostics, 300 George Street,
New Haven, CT 06511, USA
A polyvalent ELISA and plaque reduction neutralization tests (PRNTs)
were used to measure serum antibodies to West Nile virus (WNV) in horses
naturally exposed to or vaccinated against this flavivirus in Connecticut
and New York State, USA. Relying on a PRNT as a ‘gold standard’, the main
objective was to validate a modified ELISA containing a recombinant WNV
envelope protein antigen. It was also important to assess specificity by
testing sera from horses that had other, undiagnosed illnesses. Sera for
the latter study were obtained from 43 privately owned horses during 1995–1996.
Analyses by an ELISA and a PRNT confirmed the presence of WNV antibodies
in 21 (91 %) of 23 sera from naturally exposed horses and in 85 % of the
20 vaccinated subjects; overall results for both study groups were highly
concordant (91 % agreement). Humoral responses of naturally exposed and
immunized horses were similar. Both serological tests were useful in confirming past infections with WNV,
but there was no evidence that horses with undiagnosed illnesses were exposed
to WNV prior to a 1999 outbreak in Connecticut, USA.
3. Exercise alters the immune response to equine influenza virus
and increases susceptibility to infection
R. W. FOLSOM, M. A. LITTLEFIELD-CHABAUD†, D. D. FRENCH‡, S. S. POURCIAU,
L. MISTRIC and D. W. HOROHOV* Equine vet. J. (2001) 33 (7) 664-669
Equine influenza virus remains a major health concern for the equine
industry in spite of ongoing vaccination programmes. Previous work has
shown that the immune system of horses can be affected by strenuous exercise.
The possible adverse consequence of exercise-induced alterations in lymphocyte
responses measured in vitro was unknown. Here we demonstrate that subjecting
vaccinated ponies to a 5 day strenuous exercise programme results in a
significant suppression of their T cell-mediated immune response to equine
influenza virus as measured by decreased
lymphoproliferation and gamma interferon pro duction measured in vitro.
These same ponies also demonstrated increased susceptibility to influenza
disease following a challenge exposure to the same strain of virus. Rested
ponies that had received the same vaccine and challenge were completely
protected from disease. Our results demonstrate that exercise-induced suppression
of the equine immune response to influenza virus can be associated with
an increased susceptibility to disease.
3. Seroprevalence of antibodies to Sarcocystis neurona in equids
residing in Oklahoma
J Vet Diagn Invest 15:597–600 (2003) Bradford G. Bentz1, Katie A. Ealey,
Jennifer Morrow, P. L. Claypool, Jeremiah T. Saliki
Abstract. A sampling of equids from the state of Oklahoma produced an
estimate of seroprevalence of antibody to Sarcocystis neurona to be about
89.2%. (note: up to 96% in the Eastern Counties) This figure represents
the highest currently reported regional seroprevalence of antibody to this
organism. Regional differences in seroprevalence were found in the western
quadrants of the state relative to the eastern quadrants of the state,
with a significantly higher seroprevalence in the eastern regions. Thoroughbreds
were found to exhibit a statistically significant lower seroprevalence
as a breed group when compared with other breeds sampled.
Note from Shirley
Personally I find it is easier to give the content of a small capsule of high potency of transfer factors
to very sick dog or cat, especially if they have difficulty eating or if they
have a sensitive stomach. The canine or felinecomplete formulas contain yeast
and some dogs have a sensitivity to yeast which may give them the run. My dog
Shasta (65 pounds) was sensitive to
yeast. I gave her the transfer factors (human formula) which I think is a more
potent immune booster. I started by giving her one capsule of TF a day (I shoved a
capsule in her mouth or mixed it in her food) for 3 consecutive days. As she
did well on one capsule, I increased the dosage to 2 capsules a day (one morning
and one evening). A few weeks later, as she had recovered her health, I decreased
the dosage to one capsule a day as a maintenance dosage. Shirley
The Germ Survival Guide recommends transfer factors. This new book written by
Kenneth A. Bock, M.D., Steven J. Bock, M.D. is designed to give families and
individuals preventative strategies to use to protect against germs and environmental
threats. Transfer factors are extolled in the book as an effective way to optimize
immune system function so that personal immunity is at its best in the face
of a variety of health threats.
Transfer factors products for your cats, dogs, horses, cattle and any other
animals are the most scientifically advanced immune support supplements
ever formulated to keep all of your animals healthy and happy. Your animal's
immune system functions just like yours does. It is responsible for keeping
your animal healthy. There is nothing on the market that can help support
their immune system like transfer factors. It has been proven in independent
studies to increase immune system function by over 430%. Whether your animals
are experiencing a particular health challenge or you just want to protect
them from future problems,
you can now do it safely with transfer factors.
How to buy Transfer Factors at Discount Price
In 2002, transfer factors was featured in the publicly televised American Medical
Review (AMR). Since 2001, transfer factors appeared in every publication of
the Non-Prescription Drugs and Dietary Supplements Physician's Desk Reference
The American Medical Review: Transfer Factors
These products have absolutely no toxicity or side effects even at
mega doses. You may increase the amounts even further to achieve the desired
level of immune efficiency.
Mange - Many normal dogs carry the mange parasite. Holistic
veterinarians believe that it becomes a problem and spreads through
the skin when there are immune problems, inherited skin defects or illness
for other reasons. Holistic treatments aim to improve the general health,
particularly the immune system, and to homeopathically treat the inherited factors.
Demodectic Mange Mites are Common Flora in Man and Animals
Dr. Will Falconer DVM - "...
it’s a fact: we all have demodectic mites as residents on our skin.
Why aren’t we all itchy and broken out with eruptions? Only one reason:
the immune system keeps these parasites in check. So, when a dog is
diagnosed with demodectic mange, and he’s got crusty patches around
his face or toes or all over, what that means, first and foremost, is
that his immune system needs help! Unfortunately, the common treatment
is to dip the affected dogs in very toxic chemicals to kill the mites.
So toxic, in fact, that the personnel dipping the dog wear rubber gloves
andaprons! This has never made sense to me, as we
know poisons have a clearly detrimental effect on the immune system.
Wouldn’t it make more sense to strengthen the immune system and thereby
get the normal flora of mites back in control? It can be done, and transfer
factors would be the best course. To discourage mites topically, paint
on lavender essential oil, diluted 1:10 with almond oil. This can be
applied twice a day. Be sure to avoid the eyes, however. You’ll need
to give this regimen time, from at least a few weeks to a few months.
And, again, don’t short change nutrition, avoid vaccines,
and work with your homeopathic veterinarian to improve health and cure
the underlying illness that allowed the immune system to get so sluggish.".
The key to self-healing is a strong defense system
Rob Robertson, M.D. - "Nearly everything that goes wrong with
us and our pets, with the exception of trauma - i.e. broken bones, etc.,
can be traced directly to an immune system failure". Pollution, drug overload
and nutrient-poor diets compromise our immune health. The key to self-healing
is a strong defense system, which protects dogs and cats from everything
from the flu germs to cancer cells. More than their mainstream counterparts,
holistic veterinarians believe that a weak immune system plays a key role
in causing disease. Drugs aren't the answer for immune enhancement. The
immune system is not responsive to drugs for healing. Antibiotics fight
infection, but they don't affect whatever weakened the immune system in
the first place. This is why holistic veterinarians focus less on things
that cause diseases and more on those that affect the body's defenses.
Do you have a question about holistic animal health or need assistance?
Call 323-522-4521 or 323-989-3372