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Holistic Research for Alzheimer's Disease, Dementia, Memory Loss

Studies show that Dementia, memory loss and confusion associated with Alzheimer's disease may be the result of potent interplay between intestinal microbes and the brain, essential dietary deficiency, and toxicity. The brain produces new brain cells throughout our entire lives, a process called neurogenesis. Recent discoveries in the field of neurogenesis reveal the secrets to radically improve your brain’s health resulting in powerfully improved memory, learning and cognitive enhancement.

Alzheimer’s Drugs Offer No Help

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder 
linked to dementia, memory loss, confusionAlzheimer’s disease implicates symptoms of dementia, memory loss and confusion. It is a slow, progressive illness that damages nerve cells in the brain. Symptoms gradually get worse over time as more brain cells are destroyed. Though people can have Alzheimer’s in their 30s, 40s, and 50s, the disease is most prevalent in people over age 65

A study from the New England Journal of Medicine titled "Alzheimer’s Drugs Offer No Help." “The drugs most commonly used to soothe agitation and aggression in people with Alzheimer’s disease are no more effective than placebos for most patients, and put them at risk of serious side effects, including confusion, sleepiness and Parkinson’s disease-like symptoms, researchers are reporting today.”


The Alzheimer's Association has developed a list of ten warning signs of Alzheimer's disease:

  • Memory loss that affects job skills.
  • Alzheimer’s disease linked to gut bacteria depletion Difficulty in performing familiar tasks.
  • Problems with language.
  • Confusion about time and place.
  • Poor or diminished judgment.
  • Problems with abstract thinking.
  • Misplacing of things.
  • Changes in mood or behavior.
  • Changes in personality.
  • Loss of initiative.

Neurogenesis, Adult Brain Cells Do Keep Growing



Neurogenesis The apocryphal tale that you can't grow new brain cells just isn't true. Neurons continue to grow and change beyond the first years of development and well into adulthood, according to a new study. The finding challenges the traditional belief that adult brain cells, or neurons, are largely static and unable to change their structures in response to new experiences.

"Back in medical school we were told that we were given a certain number of brain cells and that was it for life. However, this idea that humans do not grow new brain cells is now fully demonstrated to be wrong. How exciting it is that we possess the ability to grow brain cells, a process called neurogenesis. Not only that, but we retain this ability throughout our entire lifetimes." David Perlmutter MD

Glutathione Role in Neurodegeneration Diseases

There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease, Dementia and memory loss may involve the generation of reactive oxygen species and mitochondrial dysfunction.

Natural Healing for WomenHere, we review the evidence for a disturbance of glutathione homeostasis that may either lead to or result from oxidative stress in neurodegenerative disorders. Glutathione is an important intracellular antioxidant that protects against a variety of different antioxidant species. An important role for glutathione was proposed for the pathogenesis of Alzheimer's disease, because a decrease in total glutathione concentrations in the substantia nigra has been observed in preclinical stages, at a time at which other biochemical changes are not yet detectable.

Because glutathione does not cross the blood–brain barrier other treatment options to increase brain concentrations of glutathione including glutathione analogs, mimetics or precursors are discussed. Schulz, J. B., Lindenau, J., Seyfried, J. and Dichgans, J. (2000), Glutathione, oxidative stress and neurodegeneration. European Journal of Biochemistry, 267: 4904–4911. doi: 10.1046/j.1432-1327.2000.01595.x

Dr. Jimmy Gutman, MD - "Clinical evidence links low glutathione levels to the most common illnesses of our time as well as newly emerging diseases. Glutathione levels diminish as we age and many diseases normally associated with aging have been linked to glutathione deficiency." .

Glutathione levels fall even much further in later stages, the magnitude of reduction in glutathione seeming to parallel the severity of the disease. The lowered glutathione values and increased oxidative stress are thought to be responsible for the loss of dopamine producing cells in the substantia nigra in Alzheimer's and Parkinson’s disease patients . The use of antioxidants, particularly Immunocal for the treatment of neurodegenerative diseases is an obvious consideration.

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Toxic Overload Linked to Alzheimer’s Disease

Researchers believe that the actual cause of Alzheimer’s disease is due to toxic metals that leaches from mercury-silver amalgam dental fillings. Dr. Boyd Haley, Dr. Murray Vimy, a dental researcher from the University of Calgary, Canada, and member of the World Health Organization (WHO), and Dr. Fritz L. Lorscheider reasoned that because mercury vapor from amalgam fillings is absorbed into the sinuses and goes through the blood stream directly to the brain it also is a basic cause of Alzheimer’s.

The world we're living in today is a toxic minefield from vaccines to pesticides to antibiotic-laden foods to mercury-poisoned fish to pollution both indoors and outdoors. Toxic metals can cause or contribute to Alzheimer’s disease, dementia, memory loss, confusion and other brain and neurological disorders.

Toxic Overload in Alzheimer's disease - How to DetoxDr. Steve Nugent PhD - "Without exception, every North American now has in his or her tissues 300-500 known toxins that were not in existence before 1940."

In 1994, the New York Times reported a scientific study which revealed that aluminum and fluoride in water could be responsible for the alarming increase in Alzheimer's Disease and percentile dementia. This confirmed the long-held suspicion of environmental writer George Glasser that fluoride has the ability to act synergistically with other toxic minerals in drinking water.

In 1995, attention was drawn to the possible link between electromagnetic radiation and Alzheimer's disease following a landmark publication in the American Journal of Epidemiology by researchers at the University of Southern California School of Medicine. Subsequently, these researchers confirmed a direct relationship between occupations exposing individuals to higher levels of electromagnetic radiation and the risk of developing Alzheimer's disease.

Their report, published in the December 1996 issue of Neurology, revealed a substantial increased risk of developing Alzheimer's disease, dementia, memory loss and confusion in individuals whose occupations exposed them to higher than average levels of electromagnetic radiation. The occupations determined to be "high risk" with respect to exposure included electrician, machinist, machine operator, seamstress, sewing factory worker, sheet metal worker, typist, keypunch operator, welder, machine shop worker, and several others. The risk of developing Alzheimer's disease in these individuals was calculated to be as much as four times higher than the general population. Subjects evaluated were at least 65 years of age. at the time of their first examination and their recorded occupations reflected what they had been doing up to 40 years prior to their evaluation and diagnosis of Alzheimer's disease.

Modern cosmetics contain a host of dubious ingredients that would be more at home in a test tube than on our faces.Coal tar colors, phenylenediamine, benzene, even formaldehyde, are just a few of the synthetic chemicals commonly included in cosmetics, shampoos, skin creams and blushes - toxins which are absorbed into your skin with every use.

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Three Potential Causes of Memory Loss:

60% of Alzheimer's Patients put on anti-psychotic drugs

Around 60 per cent of Alzheimer’s patients are put on an anti-psychotic, even in the early stages of the disease, in order to control behavior such as aggression. This effect has earned the drugs the epithet of “the chemical cosh”. The drugs can cause a serious deterioration within six months, and new research is exploring the suspicion that the drugs are also increasing the death rate among Alzheimer’s sufferers. Researchers from King’s College London and the Universities of Oxford and Newcastle made the discovery when they observed the progress of 165 Alzheimer’s patients in care homes. The anti-psychotics reviewed by the research study were thioridazine (Melleril), chlorpromazine (Largactil), haloperidol (Serenace), trifluoperazine (Stelazine) and risperidone (Risperdal). Public Library of Science Medicine, 2008; 5: e76 doi:10.1371/journal.pmed.0050076.

Soy products may be dimming memory

Home base business opportunityFrequently consuming foods containing soy may contribute to memory loss, British experts say. Experts at England's Loughborough and Oxford Universities researched the impact of soy consumption in 719 senior citizens on the Indonesian island of Java, the Daily Mail reported Saturday. Researchers determined people who ate soy at least twice a day had 20 percent less memory function that those who ate it significantly less. "Soy consumption is on the increase in the West and is often promoted as a 'superfood.' Soy products are rich in micronutrients called phytoestrogens, but it is not entirely clear what their effect on the aging brain is," said Professor Eef Hogervorst of Loughborough University. Hogervorst said vegetarians and elderly women seemed to be highly susceptible to potential memory loss from soy consumption.

Other potential causes of memory loss

Renowned neurologist David Perlmutter, MD, argues that gluten and carbohydrates are at the root of Alzheimer's disease,. And not just unhealthy carbs, but even healthy ones like whole grains can cause Alzheimer, dementia, ADHD, anxiety, chronic headaches, depression, and much more.

The vaccine for Alzheimer’s disease may cause an immune overreaction causing severe brain swelling. Some six percent of participants in a trial of the vaccine suffered from severe brain swelling, leading the vaccine manufacturer, Elan, to call off the trial. Researchers examined the brain of a woman who had taken the vaccine and died after a fall in order to investigate the side effect. They found fewer plaques in the woman’s brain than in Alzheimer's patients who did not receive the vaccine.

Vitamin deficiencies have been implicated in the development of Alzheimer's disease. A vitamin B-12 deficiency is particularly serious as it can mimic the symptoms of Alzheimer's disease and may even progress to Alzheimer's disease itself. One recent study found that 40% of elderly Americans suffers from a vitamin B-12 deficiency. People who have had surgery for stomach ulcers are particularly prone to a vitamin B-12 deficiency. Lack of vitamins A, E, and beta-carotene has also been linked to the development of Alzheimer's disease. British researchers found that Alzheimer's disease patients admitted to a London hospital had only half the vitamin E level in their blood as did healthy, matched controls. The patients' beta-carotene levels were four times lower than that of the controls.

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Alzheimer's disease and the Gut Health Connection

A breakthrough science is offering hope that Alzheimer's disease can be prevented and reversed. A new understanding of the brain-gut-microbiome connection, creates new hope for the prevention and treatment of neurological/neuropsychiatric conditions from autism to Alzheimer's to multiple sclerosis.

The most empowering aspect to the gut-brain connection is the understanding that many of our daily lifestyle choices play a role in mediating our overall wellness. This whole-body approach to healthcare and wellness continues to show its value in our longevity, well-being, and quality of life

Our gut microbiota play a vital role in our physical and neurological health via its own neural network: the enteric nervous system (ENS), a complex system of about 100 million nerves found in the lining of the gut. Poor gut health has been linked to neurological disorders such as Alzheimer’s disease, dementia, memory loss and confusion. Disturbances in gut health have been linked to Alzheimer's Disease.

Preventing and reversing Alzheimer’s disease, dementia, memory loss and confusion. A new research report appearing in the journal, Science Translational Medicine, researchers at the Karolinska Institute in Stockholm studied the blood brain barrier in mice that were “germ free.” That means, that the mice used in this experiment did not have bacteria living within their intestines. Using highly sophisticated brain scanning technology, the researchers demonstrated that the blood brain barrier in these mice was significantly compromised, basically a situation of what we may call a “leaky brain,” and this leakiness of the barrier persisted into adulthood.

When these mice received a fecal transfer, meaning that their intestines were inoculated with the fecal material including bacteria from a healthy mouse, the permeability of the blood brain barrier was markedly improved.

While it may not be currently approved by the FDA, or even a mainstream treatment in general, fecal transplant offers a powerful means of resetting the gut microbiome. By simply transplanting fecal matter from a healthy host to that of an individual suffering from one of any number of health concerns (from obesity to autism to multiple sclerosis), fecal transplant offers an opportunity to re-balance the gut microbiome, and sets the stage for a return to better health. Alzheimer’s disease linked to gut bacteria depletion

In Brain Maker, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become “sick,” and how nurturing gut health through a few easy strategies can alter your brain’s destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, Brain Maker opens the door to unprecedented brain health potential.

Prevention and reveral of Alzheimer’s disease, dementia, memory loss and confusion."Given that the microbiome composition and diversity change over time, it is tempting to speculate that the blood-brain barrier integrity also may fluctuate depending on the microbiome. This knowledge may be used to develop new ways for opening the blood-brain-barrier to increase the efficacy of the brain cancer drugs and for the design of treatment regimes that strengthens the integrity of the blood- brain barrier." Professor Sven Pettersson

The recognition of the human microbiome (HM) as a substantial contributor to nutrition, health and disease is a relatively recent one, and currently, peer-reviewed studies linking alterations in microbiota to the etiopathology of human disease are few. Emerging studies indicate that the HM may contribute to the regulation of multiple neuro-chemical and neuro-metabolic pathways through a complex series of highly interactive and symbiotic host-microbiome signaling systems that mechanistically interconnect the gastrointestinal (GI) tract, skin, liver, and other organs with the central nervous system (CNS).

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The Immune Response in Alzheimer's Disease

Immune booster and modulator supplementIf you're looking for information about a specific immune booster and immune modulator product which was mentioned in this page but is no longer published here, you can Contact Shirley for the information and for assistance. (323) 989-3372

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

While many studies have explored the role of microglia in Alzheimer’s, very few researchers have asked whether a different set of immune cells called T-cells and B-cells that reside outside the brain and play a large part in autoimmune diseases might also impact Alzheimer’s.

Alzheimer’s is the leading cause of age-related dementia and is thought to be driven by the accumulation of a protein called beta-amyloid that aggregates to form amyloid plaques in the brain. Microglia, immune cells that reside in the brain, attempt to clear this buildup, but in Alzheimer’s, they appear to be fighting a losing battle.

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Mineral Deficiency Impairs Memory and Cognitive Skills

Scientists theorize that mineral deficiency subjects us to more diseases, aging, sickness and destruction of our physical well-being than any other factor in personal health. Fulvic acids consist of an immense arsenal and array of naturally occurring powerful phytochemicals, biochemicals, supercharged antioxidants, free-radical scavengers, super oxide dismutases, nutrients, enzymes, hormones, amino acids, antibiotics, antivirals, antifungals, etc. Marine phytoplankton and Fulvic Acids greatly enhance the bioavailability of important humic trace minerals. Regenerate and prolong the residence time of essential nutrients in the cells. Modify the damage or toxic compounds such as heavy metals and free radicals. Enhance the permeability for digestive, circulatory, and cell membranes. Increase the activity of a multitude of enzymes. Fulvic Acid can also be known as nature's electrolyte. It charges and restores the potential that is or once was normal to the cell, and in doing so, balances and super charges cellular life. (do not confuse "fulvic acid" with "folic acid" which is a common B vitamin).

A deep sea micro algae abundant in a wide range of nutrients such as trace elements, amino acids, vitamins, minerals, chlorophyll, enzymes and cellular materials, marine phytoplankton provides vital nutrients for brain function by boosting and supporting all systems within the body. Its antioxidants and unique polysaccharides can halt the genetic mutations that can lead to cancer. Both high levels of saccharides and adaptogens increase energy and stamina by improving our ability to consume and use oxygen. Adaptogens also improve cardiovascular health by strengthening the heart and circulation. "My 11 year old has been in a special needs school for the last 3 years, due to severe memory loss caused from seizures. Since taking Marine Phytoplankton my son no longer needs to take medication and his memory is as good as it ever was."

'Memory Herb' Helps Alzheimer's Patients

Alzheimer MythGinkgo Biloba, an herb touted as a memory booster, shows promise in treating Alzheimer's disease, a study published in the Journal of the American Medical Association (JAMA) suggests. Previous studies have shown that ginkgo improves blood flow to the brain. In Europe, there is now a large and convincing body of evidence showing how the herb Ginkgo Biloba will help boost memory and brain function, as long as the patient takes it for several months.

German researchers, for example, found that giving people who had been diagnosed with memory and learning problems ginkgo biloba significantly improved their memory skills after six weeks, and dramatically increased their ability to learn after five months. Ginkgo biloba were found to benefit cognitive, (which means learning, memory, and knowing things) function, within three months. In fact, Ginkgo is so effective that some scientists now suggest everyone over 40 should take a daily dose to help prevent the slow but inevitable decline of brainpower that is a feature of aging. In Germany, Ginkgo is the most widely prescribed herb, as it is considered to be as effective as drug treatments used for treating Alzheimer’s disease and other severe forms of memory and mental function decline.

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Essential Fatty Acids Deficiency and Alzheimer

Flaxseed oil Healing Power Omega 3 fatty acids in the form of flaxseed oil dramatically improved brain function in Alzheimer's patients with dementia and cognitive memory loss. Among various organs, in the brain, the fatty acids most extensively studied are omega-3 fatty acids. Alpha-linolenic acid (18:3omega3) deficiency alters the structure and function of membranes and induces minor cerebral dysfunctions, as demonstrated in animal models and subsequently in human infants. Even though the brain is materially an organ like any other, that is to say elaborated from substances present in the diet (sometimes exclusively), for long it was not accepted that food can have an influence on brain structure, and thus on its function.

Consequently, the nature of polyunsaturated fatty acids (in particular omega-3) present in formula milks for infants (premature and term) conditions the visual and cerebral abilities, including intellectual. Moreover, dietary omega-3 fatty acids are certainly involved in the prevention of some neuropsychiatric disorders, particularly dementia, notably Alzheimer's disease.

James Scala PHD - " Fish oil supplies omega-3 oils, and among them is docosahexaenoic acid (DHA), essential for brain and eye tissue development (specifically the retina) in infants; it remains fundamental to those tissues throughout life. Current research focuses on these oils—often woefully short, if not deficient, in modern diets—as one cause of attention deficit disorder . Once more, modern research is validating folk wisdom—fish really is brain food." The basic building blocks of our brain cells are essential fatty acids such as EPA and DHA from fish oil . These fatty acids are also used as fuel for brain metabolism and help control the chronic inflammatory processes involved in degenerative brain disorders.

A study conducted by Uppsala University in Sweden looked at the effect of Omega 3 fatty acids on patients who already had Alzheimer's disease. Researchers gave 89 patients Omega 3 fatty acids for a period of 6 months and another 85 were given a placebo in the form of corn oil. After the initial 6-month period, the placebo group also switched to Omega 3 for a further 6 months. Although there was no real differences noted between the two groups in general, there was an interesting result where 32 patients who had milder mental impairment showed less of a decline whilst taking Omega 3.

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Homeopathy can Improve Cognitive Function

Whether they are suffering from Alzheimer’s Disease or other forms of dementia, often homeopathy can, at least to a degree, help. It usually will not cure, but will often slow the decline and make their life much happier. Here is one case to give you an idea how this works:

Ruth was a woman in her early 70’s who was diagnosed with Alzheimer’s Stage 3. She had moderate level of memory loss and confusion. She talked of her fears of what was happening to her and what lay ahead. Her main concerns though were of her past life. She described a life of many hurts. Of people doing things that emotionally made her feel very bad. Of feeling alone and sorry for herself. Of all the love she felt but couldn’t always express. Of her headaches and arthritis pains.

Need help?Based upon this and many other symptoms we gave him a homeopathic dose of Natrum Sulphuricum (note this was the right remedy for her but the possibility of it being the right remedy for another person with Alzheimer’s is very low). By one month she was much happier. Her memory was much better for both the past and the present. She was much less tired. She said that she felt better than she had in years. She no longer felt so dragged down by the past.

Over the next 10 years there was a very slow gradual decline into dementia but much slower than average for Alzheimer’s patients. Whenever she didn’t feel as good she took a dose of her remedy which lifted her up for weeks. Despite the decline she was happier than she had ever been in her life. The remedy helped her memory, health and happiness tremendously and slowed but did not stop the development of the disease.

In this example you see the difference between homeopathy and other approaches for treatment of Alzheimer’s. After the right remedy we expect to see everything getting better in the person’s life. In some very early stage Alzheimer’s cases we can see complete cure. More often we see improvements as in this example.

Alzheimer's Disease Responding to AFA
Gabriel Cousens, M.D.

Presently there is a common belief that there is no cure or even amelioration for the degenerative process called Alzheimer's Disease. Having personally experienced and witnessed in my patients the brain function enhancing qualities of a blue-green algae named aphanizomenon flos-aqua (AFA), I was interested when I read some reports of its effects on Alzheimers Disease. This algae is particularly high in active neurotransmitters and appeared to have positive therapeutic results in people whose general mental functioning seemed sluggish.

For my experiment I chose two individuals who had well documented Alzheimer's Disease, dementia and memory loss. They had obvious deficient mental functioning. Each month, besides my notes, the mate of each of the patients was asked to fill out a questionnaire covering thought process, memory function, ability to focus, judgment, perception, emotions, ability to care for oneself, and sleep function. Each section had several categories to be evaluated from 1 to 10 for a total of 28 questions. Each case has been followed for 12 months.

The first case is a 66-year-old women with a seven-year history of Alzheimer's; the last five of which were thoroughly diagnosed in 1978 and followed at Stanford Medical Center. She had also been through oral choline and I.V. chelation therapy without any effect on her deteriorating state.

On initial exam she revealed a significant aphasia. She seemed unable to express her thoughts in words; her long and short tern memory was significantly degenerated; she had great difficulty focusing on the present situation. In essence she seemed absent. She also had a severe Parkinson-like tremor, had much difficulty in walking a straight line and tilted to the right.

According to the report from her husband, she was completely unable to take care of herself or even dress herself. The husband seemed hopefully pessimistic. After one month of taking the blue green algae some decrease in the aphasia was clearly discernible. A glimmer of awareness seemed to have returned to her eyes. Some of the hand tremors had also decreased. She was also able to put on an apron and tie it - something she had not done for months. She also seemed to be able to express her feelings more. By two months, her communication improved and she was able to watch TV and understand what was happening.

By six months, her husband and I both agreed on our subjective experience that her spirit, humor, and sense of awareness had significantly improved. She was now able to work intellectually with the environment. Her short term memory had improved. The aphasia had significantly improved over the past six months, but had seemed to level off in the last month. Her attention span had improved to the point that she could sit for several hours listening to music. Her judgment, reasoning ability, and clarity of thinking had significantly improved. There was no change in her long term memory. On the physical level, she had moved from not being able to dress herself to being able to put her clothes on, although sometimes backwards. She was able to walk a straight line and stand almost straight.

At 12 months, some slight improvement in these areas was noted. Her course at this point, after relatively rapid improvement in six months, seems to be a very gradual improving situation. The second case involved a 64-year-old lawyer from the Midwest who was diagnosed as having Alzheimer's in 1982 after a series of neurological and psychological tests. Before he had come for diagnosis his intellectual functioning and memory had significantly decreased. He could no longer perform his work, or remember what transpired beyond 15 minutes, and his IQ was measured at 92, significantly below that of the average lawyer. He was put on the same protocol of the blue-green algae as the first case. After one month his wife noted a cessation of the degenerative process. After 12 month, she has noted no further obvious degeneration, yet no significant return of lost function. The wife of the patient is quite pleased with the results and feels the basis of a solid husband-wife relationship has been preserved.

Two thoroughly documented cases have been reported: one showing some significant return of function and the other showing cessation of progressive degeneration from Alzheimer's. These preliminary results suggest that Alzheimers may be a degenerative process that indeed may be halted and possibly at least partially reversed by the use of aphizominon flos-aqua. " Gabriel Cousens, M.D . (Dr. Cousens is an orthomolecular psychiatrist who practices in Petaluma, California)




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