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Glyconutrients, Essential Nutrients for Humans and Animals

In test after test conducted at leading institutes around the world, Glyconutritionals (Phytonutrients, Saccharides) have been shown to lower cholesterol, increase lean muscle mass, decrease body fat, accelerate wound healing, ease allergy symptoms, and allay autoimmune diseases such as arthritis, psoriasis, and diabetes. Bacterial infections, including the recurrent ear infections that plague toddlers, often respond remarkably to saccharides, as do many viruses--from the common cold to the flu, from herpes to HIV. The debilitating symptoms of chronic fatigue syndrome, fibromyalgia, and Gulf War syndrome frequently abate after adding saccharides. And, for cancer patients, saccharides mitigate the toxic effects of radiation and chemotherapy--while augmenting their cancer-killing effects, resulting; in prolonged survival and improved quality of life. Marine Phytoplankton and Goji (Lycium) berries are a rich source of saccharides/glyconutrients.

What are Glyconutrients?

Glyconutrients Glyconutrients are not vitamins, minerals, amino acids or enzymes, but are in a class of their own as nutritional supplements derived from plants. Glyconutritional supplements are formulated based on new understanding in the biochemistry of how the human body maintains health at the cellular level. Healthy cells lead to healthy tissue - healthy tissue leads to healthy organs - and healthy organs lead to healthy bodies. Despite the relatively recent discovery of glyconutrients and their functions, medical doctors and the general public are becoming increasingly aware of their importance in treating underlying causes of disease and in maintaining good health. A glyconutritional approach gets at the root cause rather than treating only the symptoms.

There are over 20,000 studies conducted annually on glycoforms alone. Researchers from universities Oxford and John Hopkins and major pharmaceutical companies realize the importance of this new discovery. Studies confirm that the eight essential biologically active sugars can accomplish amazing results. The following are just a few examples of the exciting possibilities of Glyconutrition ( Page 20: Scientific Research Backing Glyconutrition):

  • Dramatically raises natural killer cell and macrophage count against infectious organisms.
  • Activates immune T-cell activity only when invaders or antigens are present.
  • Decreases cell death in chronic fatigue syndrome.
  • Dramatically elevates disease resistance in weakened individuals.
  • Acts as antioxidant compounds, which boost the collection of dangerous free radicals.
  • Protects the body against toxin and pollutant exposure.
  • Slows premature aging.
  • Decreases inflammation in diseases like rheumatoid arthritis.
  • Helps immune cells recognize invaders due to a mutual “sugar exchange” of information.
  • Enables cellular components to stick to each other initiating the right reactions.

Glyconutrients - The Missing Link? (PDF - 3.2Mb) - 5 page article published in "Positive Health" Magazine Feb 2002

Martin Milner, N.D., - "We are finding glyconutrient deficiencies associated with a large range of diseases."

Dr. John Rollins - "Glyconutrients are one of the most important healthcare discoveries of the 21st century." Dr. Rollins is the former Assistant Professor of Microbiology at Howard University’s School of Medicine

Dr. M. Schlachter, MD; - "The Biggest revolutionary change in the war against disease is represented by Glyconutrients"

Glyconutrients, Vital Sugars to Your Health

Dr John Axford - "Sugars are going to be the molecules of the future. Glycobiology is one of the last frontiers of science to be conquered and is going to be at the cutting edge of a large number of discoveries and therapies over the next decade." Dr Axford is; immediate past-President of the Royal Society of Medicine, Section of Clinical Immunology and Allergy.

Putting the terms "sugar" and "health" together seems almost like a paradox, but emerging evidence shows that certain types of sugars - commonly called saccharides or glyconutrients - are responsible for fighting off disease and maintaining overall health. These sugars have been shown to reverse autoimmune disorders and diabetes, ease allergy symptoms, lower risk of heart disease, and improve overall function of the body's immune processes. Common infections, including cold, flu, ear infections, and herpes, respond well to use of saccharides, as do symptoms of fibromyalgia, chronic fatigue and lupus. Even cancer patients have found gylconutrients to enhance traditional treatments while lessening their debilitating side effects.

The sugars found on all glyconutrients saccharides also address the workings of the brain and nervous system – from memory and sleep to anxiety and depression. In addition, they have a role in helping the body handle cholesterol and fats by lowering triglycerides and low-density lipoproteins (LDL) while, at the same time, raising the good cholesterol (HDL). Commercials have long touted the benefits of eating oatmeal to bring down cholesterol. What is not mentioned is that it is the sugars (beta-glucans) in oatmeal that are responsible.

Another important essential sugar function (saccharides); is to help retain bone density and muscle mass. The body undergoes wear and tear as it ages. Cells and tissues need to be replaced, remodeled, and renewed continually. Exercise helps the body to develop new blood vessels while increasing muscle mass. Certain kinds of tissues adapt to exercise by increasing the size and number of cells. Adaptation, healing, and recovery are all forms of tissue remodeling. Essential sugars play important roles in these processes.

There is so much potential to these sugars (saccharides); that it is mind-boggling. What is included here is only just the beginning of what is to come. The excitement that must have reverberated when penicillin was developed is nothing compared to the excitement as science continues to find out all the capabilities of this maligned substance. This is not a gimmick or a fad but the actual foundation upon which other nutrients can build. We will all have to stay tuned.

Without the proper nutrients, our organs and body systems begin a slow process of degeneration. Degenerative diseases are the leading cause of death in this country, and are growing dramatically. Cancer, diabetes, heart disease, arthritis -- these are degenerative processes that cause immeasurable human suffering. In addition, emotional stress in the 20th Century is at an all time high and directly impacts our well-being. Glyconutrients can replace the precious nutrients missing in today’s food supply. They can provide superior nutritional support for total body health. Taken daily, they supply your organs and body systems with a rich density of chemistry, nutrition and raw materials that helps them to repair, regenerate and function at their best.

When used along with surgery, chemotherapy, and/or radiation, glyconutrients (saccharides); have proven to help lessen the side effects of these treatments while helping the body to recover and heal itself more quickly than if only the treatments were implemented. More studies are now underway due to the breakthrough findings in this initial research period. In fact, The National Institutes of Health in the Fall of 2001 awarded The Scripps Research Institute in San Diego, CA a $34 million grant to understand how cells and the immune system use these sugars. Science Magazine in March, 2001 dedicated the major part of an issue to summarizing the extensive research currently underway in the field of glycobiology and the great potential health benefits in applying this new understanding.

Healing Power of SugarsThe Healing Power of Sugars covers many subjects ranging from the use of glyconutrients during pregnancy, to child development issues to sports medicine, inflammation and disease cases. The science of glyconutrients is very technical, yet these doctors do a remarkable job of bringing the science down to a lay level without neglecting the concerns and issues that will appeal to the medical and scientific audience as well. According to the Massachusetts Institute of Technology Review, February 2003, "If you don't have glycosylation, you don't have life."

Dietary saccharides (healthy sugars) are not only a source of energy, they also serve important structural and functional roles in the human body. Consumption of fresh, unprocessed plant foods, which contain free monosaccharides and polysaccharide fibers, is strongly correlated with numerous health benefits, including protection from diabetes, heart disease, and cancer. The health benefits conferred by monosaccharide consumption are gaining increased attention. The benefits of polysaccharide fiber consumption are largely based on the mechanical abilities of fiber to bind toxins, add bulk to feces (which speeds intestinal transit time), influence intestinal nutrient absorption rates (which modulates plasma glucose levels), and bind bile acids (which lowers plasma cholesterol levels).

Scientists have recently discovered that our modern diet is missing some very vital nutrients, and surprisingly enough, these missing nutrients are essential fatty acids (ie: omega 3 fatty acids as in flaxseed oil and fish oil); and essential sugars (glyconutriens/>saccharides). Now scientists and nutritionists are just beginning to understand that there are essential sugars as well. Eight essential sugar compounds function individually as building blocks to assemble a nearly infinite variety of complex molecules known as glycans or sugar chains.; The bad news is that we are only getting; two of the eight monosaccharides (glucose and Galactose) in our modern day diets. More and more researchers and informed doctors have concluded that this deficiency is one of the major contributing factors to our declining immune system function and the corresponding dramatic increase in disease. Glyconutrients research field has been in numerous peer reviewed articles and text such as Harper's Biochemistry, Acta-Anotomica (has the latest tech grad level research in cellular biology - published in Europe), Science Magazine, and Positive Health" Magazine.

Source of Glyconutrients

Do you have a question about holistic health or need assistance? Email Shirley or call 323-522-4521

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Optimum Cell-to-Cell Communication

Dr. Hugo Rodier M.D. - "Most of the Nobel prizes in Medicine and Biology have been awarded to the concept of “cell communication,” which is how our 100 trillion cells get their metabolic function coordinated (J. Science, November 26th, 2004.) They do this through a system of “messages,” which are well-known molecules like hormones, neurotransmitters, enzymes, etc. They form a vast network of communication, which should have never been separated into different components. The Psycho-Neuro-Immune-Endocrine system of cell communication to coordinate our metabolism is now considered to be the cornerstone of health and function in cutting edge research (“The intricate interface between the immune system and metabolism,” J. Trends in Immunology 2004;25:193.)

Cell communication takes place mostly at the level of the outer cell membrane, which is equipped with antennae, or radar-like glycoproteins. These “receptors” are literally shaped into “lock-like” structures, by the energy produced within the cells themselves. Messages turn out to be “key-like” glycoproteins, or molecules that will need to match the lock, or receptors on the cell membranes for “listening “ to occur. The mitochondria are specialized organelles in charge of producing the energy necessary to fuel all activity within the cell. Mitochondria function takes place mostly in their own cell membranes, too. While the nuclei are very important to all cells, they are only a blue print to guide the production of each cell. The messages therein produced, are sent from the cell membrane, and received by other cells’ membranes throughout the body (J. Science, May 31st, 2002 ? 2003;300:1461-1604.)

Naturally, the cell membrane becomes an extremely important part of cell communication and function. The cell membrane is the very interface between each cell and its environment. Cells are totally dependent on the environment in our bodies. Said environment is created by our very lifestyles. Poor foods, polluted air and water, poor relationships, etc, provide toxic environments, thereby compromising cell membrane function (“The Biology of Belief,” Bruce Lipton, 2005 ? “Quantum Cellular Biology,” J. Medical Hypothesis 2001;57:358.)

So, the structure and function of our cell membranes is extremely important for our receptors to successfully receive the messages generated from other cells, thus coordinating our cells’ metabolism and function. And, what are our cell membranes made up of? Sugars, proteins and fats! In other words, nutrition provides not only the fuel needed for our cells to function, but also the very molecules our cells need to be structured properly. A failure to eat properly will result in practically all manner of diseases. No wonder that “food is the best medicine!” (“Life’s Complexity Pyramid,” J. Science 2002;298:763.)

The wrong sugars (processed,) fats (saturated and tranhydrogenated,) and proteins (animals exposed to many toxins) will compromise cell membrane structure and function. As noted above, this compromises cell communication, AND thusly, the ability of each cell to produce energy. Simply put, all cell function will then be compromised, and practically all diseases will manifest themselves. This is why the right foods, those foods which contain the most healthy sugars, fats, and proteins will support body function and structure better than less gifted foods.

A classical example of a “failure to communicate” (think of “Cool Hand Luke”) at the cellular level is Insulin resistance, the scourge of our modern days. Simply put, our cell membranes throughout the body are becoming rigid and inflexible, because of poor dietary intake, environmental pollution, and stressful lifestyles, thus compromising response to the most important metabolic messenger: insulin. Insulin finds the receptors and the cell membrane of our cells somewhat unresponsive, which can trigger practically all diseases (“Second world congress on the insulin resistance syndrome,” J. Diabetes Care 2005;28:2073.)

We can say that consumption of refined sugars, which is rampant and addictive in our society, constitutes a source of toxicity to the cell membranes. With these types of foods, cell membranes also become inflamed, since they lack the micronutrients to quell the fire produced by our metabolic furnaces. These processed foods lack antioxidants to neutralize all the oxidating free radicals produced by our metabolic furnaces, and`by toxins in the environment. Thus, our cell membranes also become oxidized. Since the mitochondria (our cell furnaces) also depend on healthy cell membranes (composed of the right sugars, fats, and proteins) to produce energy, or metabolize, poor nutrition will cause mitochondrial dysfunction: These are the most basic mechanisms known in modern medicine (J. American Medical Association 2004;291:358.

Do you have a question about holistic health or need assistance? Email Shirley or call 323-522-4521

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Glyconutrients and Stem Cell Production

Dr. Reg McDaniel talks about first seeing new stem cells in the peripheral blood of clients using glyconutrients many years ago and not recognizing these cells as stem cells. They were 10 times the size of white blood cells and they were given the name "Gee" cells for some time as that's what Dr. Reg said when he observed these new cells that no one could identify! Now we have the tools to identify these cells appropriately as stem cells which can be used as "master keys" to move to places in the body as the body calls for. About a year ago there was an article in JAMA regarding the stem cells implants of male cells into female bodies of women with leukemia who had received a stem cell transplant. When these women died, male marked cells were found as neurons in the brain.

Dr. Reg realized that this might offer an explanation in the many children with fetal alcohol syndrome that were doing so well with the glyconutrients and others who had advanced so far beyond their perceived genetic limitations. He told the story of several adopted aboriginal children in Canada who had fetal alcohol syndrome who have done remarkably well, improving from IQ's estimated to be around 50 to levels around 100. One girl who had difficulties with reading and numbers and was in remedial classes after 3 years with glyconutrients was able to read a Harry Potter book in a week and discuss what she had read.

When they measure the before and after stem cell counts in the blood, virtually none are detectable prior to glyconutrieints. Within a week of giving glyconutrients, there are 200-400 stem cells seen in a microliter of blood with about 5-10 thousand white blood cells. If one extrapolates to the whole;body, it is possible that there are 1.7-3 trillion new stem cells throughout our body as we add in glyconutrients. We're at the beginning of understanding all of what is possible with stem cells. There is an article in the June Scientific American if you want to read more about stem cells.

Source of Glyconutrients

Do you have a question about holistic health or need assistance? Email Shirley or call 323-522-4521

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The Missing Nutrients

glyconutrients - missing nutrients Dr. Jerry Tennant, M.D. says that marine phytoplankton, a rich source of glyconutrients, contains almost everything one needs to sustain life and to restore health by providing the raw materials to make new cells that function normally. Marine phytoplankton has been called "the most nutritionally dense foods on the planet". Containing a wide range of trace elements, amino acids, vitamins, minerals, chlorophyll, enzymes and cellular materials, marine phytoplankton promotes and maintains optimum health by boosting and supporting all systems within the body. Its antioxidants and unique polysaccharides can halt the genetic mutations that can lead to cancer. Both high levels of saccharides and adaptogens increase energy and stamina by improving our ability to consume and use oxygen. Adaptogens also improve cardiovascular health by strengthening the heart and circulation.

Michael D. Schlachter, M.D; "After seeing the benefits and noting the scientific validation of these nutrients, I no longer consider the addition of proper nutrients to the diet as a luxury.; It is a fundamental and integral part of helping my patients achieve and maintain the health that they want and deserve. The biggest revolutionary change in the war against disease is represented by glyconutrients. If you do not want to become a patient (and therefore a statistic) you need to answer in your own mind and heart if what you are doing for your health is optimal, and if not what else can you do."; Michael D. Schlachter, MD, is on the Board Certified Internal Medicine and Pulmonary Disease, Clinical Instructor at the University of Nevada Medical School.

Susan Lord, M.D - "Glyconutrients came to my attention, actually, about two years ago, when I was working with a patient with hepatitis-C. I had pulled out all of the stops with her, and I was getting nowhere, and her health condition was deteriorating before my eyes, to the point that she was nearly bedridden. Working on the Internet, she came across these products called glyconutrients and started taking them. She stopped everything that I gave her and started;nothing but these, and her health started improving immediately, to the point where she is in excellent health today. That got my attention. Last year for our cancer conferences, I did more research on these supplements. I understood that they seemed to be helping cancer patients who had gone through chemo and radiation. It helped them with quality of life and keeping their blood counts up. Last year at the cancer conference, we invited Dr. Glen Holland (?), who is an oncologist from the Midwest, to come and to give a very, very preliminary presentation about these compounds. It was a little more than anecdotal. He did have some data, but it was very preliminary. But it looked promising."

Angie's stage 3 cancer recovery with glyconutrients: "My surgery was September 29th. I started taking glyconutrients before surgery but only what the bottle recommended. After surgery and the pathology report came back, I started taking a lot more because of the state I was in, (stage III). I went back in for a scan in December, 6 weeks after taking the larger amounts, and the two areas of tumor that were remaining after surgery were gone. I could not believe it. My oncologist could not compare with the previous scan, but my surgeon said, “Hmm, this looks much better than what I expected.” So, I continued with the glyconutrients and other products. I went back in for a scan in March and my oncologist said , “Your scans look great. Keep taking your glyconutrients and we’ll see you in another three months.” My surgeon said, “Scans look great. There is no tumor, no edema (swelling). This is what we want and hope to see, but don’t always get it.” Again I was very excited. I did not completely ignore my doctors, I simply put their treatment plan on hold, while I pursued another path less harmful to my body. I still go in for scans every three to four months as they recommended. In the show I was quoted at the end of program saying the doctor told us “there wasn’t much change.” That quote was my doctor indicating there wasn’t much change from the December scan to the March scan. That’s because they were both good scans!

Do you have a question about holistic health or need assistance? Email Shirley or call 323-522-4521

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Matthew Silver, MD; - "An associate in her early fifties who had suffered for many years from the toxic effects of chlorine poisoning from inhaling vapors from an over-chlorinated swimming pool. This had resulted in many severe health challenges including extreme chronic fatigue and breathing difficulty that kept her housebound and dependent on oxygen. Even minimal exertion led to extreme shortness of breath. After just three days of drinking Goji juice, she reported that all of her symptoms improved dramatically and that she was able to leave her house without oxygen and work in her garden, which she had not been able to do in years.

Rock-solid scientific evidence discovered at major universities around the globe back up the historical usage of the Goji berry with 71 different studies now published proving its benefits. One of the most exciting things about the ongoing research is that more and more studies on the Goji berry are being published each year, including 11 published in 2004, 9 published in 2005 and 4 more already published in 2006! These studies cover many aspects of health including the brain, vision, immune system enhancement, and many others. You can view abstracts of these studies by going to www.pubmed.org, the United States Government sponsored Website, and typing in the Latin name for the Goji berry, Lycium barbarum.

Goji berries and marine phytoplankton contain important phytonutrient compounds, that work in the body as directors and carriers of the instructions that cells use to communicate with each other. These polysaccharides are “Master Molecules” that command and control many of the body’s most important defense systems. Goji of Himalayan quality exhibits a balanced polysaccharide profile and a uniquely potent Spectral Signature.

Dr. John Axford, MD, leading expert in this new field of glycobiology and President of Clinical Immunology, Royal Academy of Medicine, stated at a health conference last year, “Sugars are going to be the molecules of the next decade.  Glycobiology is one of the last frontiers of science to be conquered and it’s going to be at the cutting edge of a large number of discoveries and therapies over the next decade.” Ancient Chinese healers have been using this Goji berry for centuries ...and time has proven its effectiveness in the anti-aging category... however science has just now begun to explore all of its properties.

"The results that I have seen with hundreds of people are truly astonishing... I consider Goji Juice the cornerstone of my approach to health and vitality. Virtually every one of your important physiologic systems can benefit from Goji." - Dr. Ron Friedman, M.D., residency done at Harvard Medical School

"I would recommend Goji Juice to practically anyone. The results I have seen are nothing short of astonishing."; - Dr. Marc Westaway, M.D., University of Queensland Medical School

"In the 25 years I've worked in the wellness industry, I've never seen nor experienced greater benefit than I have with Goji Juice. I don't think it's unreasonable to call Goji, literally, the Fountain of Youth."; - Dr. Sandra Lee Boice, M.S., Ph.D. in Clinical Nutrition

"Although my personal benefits from drinking Goji Juice have been quite impressive, the results that others with whom I have shared it with have often been absolutely astounding. The Goji berry is nature's perfect food because it has such a high density of nutrients."; - Dr. Matt Silver, M.D., Family Practice physician with more than 18 years clinical practice

Lycium barbarum (the Latin name for the Goji berry) "Traditionally the Goji berry has been used to treat inflammation, skin irritation, nose bleeds, aches, pains and as a sedative. It is also commonly used with other botanicals in Chinese medicine for poor vision, anemia, and cough. A polysaccharide isolated from lycium has been shown to have anti-tumorigenic, immune enhancing, and hepatoprotective properties in vitro. It also showed radiosensitizing effects in mice. Data from an observational study done in China in 1994 involving 75 cancer patients suggest that Lycium Barbarum Polysaccharides may be beneficial when used with certain cancer treatments. However, well designed clinical trials are needed to verify this effect. It is also unclear if similar effects can be observed with cancer treatments that are currently in use."

Lycium barbarum is undergoing intense scrutiny as an anti-malignant drug in Tibet, Mongolia, China, Japan and Switzerland.; It has been found that the fruit, as well as an extract from its leaves, can kill many kinds of; malignant cells in vitro.; In vivo studies and human studies are proving to be highly promising.; Goji Juice (lycium barbarum) contains approximately 124 ppm of organic Germanium.; Germanium has been demonstrated to have anti-malignant activity. Japanese studies indicate that organic Germanium is effective in treating liver malignancy, lung malignancy, uterine malignancy, cervical malignancy, and testicular malignancy when combined with other drugs.;; It has been found to induce the production in human beings of g-interferon. Interferon can depress and even kill malignant cells.; Germanium possesses the power to take over the hydrogen ion from malignant cells. Losing hydrogen ions can cause depression and even death to malignant cells.; Besides Germanium, this berry has other components that act against malignancy. These other components appear to be able to depress or block the synthesis of the malignant cells' DNA, which interferes with the cells' ability to divide and thus lowers the reproductive capacity of the malignant cells.

In Asia, the Goji berry (Lycium barbarum) has been used as a primary allergy therapy for centuries. The noted ethnobotanist, Dr. James A. Duke, classifies Goji as an immunomodulator — an enhancing substance that can balance and normalize abnormal immune response. The Mongolian Institute of Traditional Medicine reported that Goji has been used in the treatment of atrophic gastritis, weakened digestion due to reduced stomach activity.; Patients consumed 10 grams of the whole fruits each time, three times daily before meals for two months and longer with excellent results.; Goji Juice contains 8 kinds of amino acids (six times higher than bee pollen), of which 8 are indispensable amino acids for the human body (such as isoleucine and tryptophan).; 50% of the each Goji berry's amino acids are free amino acids.; Goji Juice contain 21 trace minerals, (of which the main ones are zinc, iron and copper) and 500 times the amount of vitamin C by weight than oranges.; Goji Juice is loaded with vitamin B1, B2, B6 and vitamin E. Mature fruits contain about 11 mg. of iron per 100 grams, as well as glucose, fructose, vitamin C, beta-sitosterol (an anti-inflammatory agent), linoleic acid (a fatty acid), sesquiterpenoids (cyperone, solavetivone), tetraterpenoids (zeaxanthin, physalin), and betaine (0.1%).

Source of Glyconutrients, Saccharides

  • Fulvic minerals - Scientists theorize that mineral deficiency subjects us to more diseases, aging, sickness and destruction of our physical well-being than any other factor in personal health. A great many known aliments, around 60, are directly linked to mineral deficiency. Organic fulvic acids are created by micro-organisms in the soil, for the purpose of transporting minerals and nutrients from the soil into the plant. Muco-polysacharrides (complex carbohydrate sugars) flow throughout the plant for nourishment. Some are returned to the roots.
  • Dr. Jean Marcoux M.D - "Almost everyone I put on Immunocal tells me that they feel better as soon as they start taking the product. This is explained by the fact that Immunocal brings to all the cells in our body, the building blocks necessary to produce glutathione, a small protein that each cell needs to function properly. In severe asthmatics taking Immunocal, the attacks become less frequent and less severe. The need for medication is decreased, they sleep better, they don't miss work or school as often, resulting in a better quality of life." Dr. Jean Marcoux is a Board Certified Allergist, Immunologist
Do you have a question about holistic health or need assistance? Email Shirley or call 323-522-4521
Scientific References
  1. Toyoda-Ono Y, Maeda M, Nakao M, Yoshimura M, Sugiura-Tomimori N, Fukami H. 2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit. J Agric Food Chem. 2004 Apr 7;52(7):2092-6.
  2. Breithaupt DE, Weller P, Wolters M, Hahn A. Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. Br J Nutr. 2004 May;91(5):707-13.
  3. Cheng CY, Chung WY, Szeto YT, Benzie IF. Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial. Br J Nutr. 2005 Jan;93(1):123-30.
  4. Wu SJ, Ng LT, Lin CC. Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res. 2004 Dec;18(12):1008-12.
  5. Zhao H, Alexeev A, Chang E, Greenburg G, Bojanowski K. Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts. Phytomedicine. 2005 Jan;12(1-2):131-7.
  6. Gan L, Zhang SH, Liu Q, Xu HB. A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. Eur J Pharmacol. 2003 Jun 27;471(3):217-22.
  7. Gan L, Hua Zhang S, Liang Yang X, Bi Xu H. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int Immunopharmacol. 2004 Apr;4(4):563-9.

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